Chromatin Dynamics in the Regulation of CFTR Expression
Abstract
The contribution of chromatin dynamics to the regulation of human disease-associated loci such as the cystic fibrosis transmembrane conductance regulator (CFTR) gene has been the focus of intensive experimentation for many years. Recent technological advances in the analysis of transcriptional mechanisms across the entire human genome have greatly facilitated these studies. In this review we describe the complex machinery of tissue-specific...
Paper Details
Title
Chromatin Dynamics in the Regulation of CFTR Expression
Published Date
Jul 13, 2015
Journal
Volume
6
Issue
3
Pages
543 - 558
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