Neutrophil activity in chronic venous leg ulcers—A target for therapy?

Chronic venous leg ulcers ( CVLU s) affect approximately 600,000 people annually in the United States and accrue yearly treatment costs of US$2.5–5 billion. As the population ages, demands on health care resources for CVLU treatments are predicted to drastically increase because the incidence of CVLU s is highest in those ≥65 years of age. Furthermore, regardless of current standards of care, healing complications and high recurrence rates...