Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics.

Volume: 58, Issue: 6, Pages: 1323 - 1337
Published: Jun 1, 1996
Abstract
The introduction of stochastic methods in pedigree analysis has enabled geneticists to tackle computations intractable by standard deterministic methods. Until now these stochastic techniques have worked by running a Markov chain on the set of genetic descent states of a pedigree. Each descent state specifies the paths of gene flow in the pedigree and the founder alleles dropped down each path. The current paper follows up on a suggestion by...
Paper Details
Title
Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics.
Published Date
Jun 1, 1996
Volume
58
Issue
6
Pages
1323 - 1337
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