Metabolism of amyloid β peptide and pathogenesis of Alzheimer's disease.

Volume: 89, Issue: 7, Pages: 321 - 339
Published: Jul 25, 2013
Abstract
The conversion of what has been interpreted as “normal brain aging” to Alzheimer’s disease (AD) via transition states, i.e., preclinical AD and mild cognitive impairment, appears to be a continuous process caused primarily by aging-dependent accumulation of amyloid β peptide (Aβ) in the brain. This notion however gives us a hope that, by manipulating the Aβ levels in the brain, we may be able not only to prevent and cure the disease but also to...
Paper Details
Title
Metabolism of amyloid β peptide and pathogenesis of Alzheimer's disease.
Published Date
Jul 25, 2013
Volume
89
Issue
7
Pages
321 - 339
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