Large scale isolation of functionally active components of the human complement system.
Abstract
In the present work a scheme is presented for the isolation of multiple components of human complement in a functionally and biochemically pure state and with full hemolytic activity. These preparative procedures allow high recovery of milligram and gram quantities of particular complement components from a large pool (2-11 liters) of fresh EDTA plasma in no more than four chromatographic steps. Many components (C3bINA, C5, C3, C1EI, C4, and C9)...
Paper Details
Title
Large scale isolation of functionally active components of the human complement system.
Published Date
Apr 1, 1981
Volume
256
Issue
8
Pages
3995 - 4006
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