Cellular effect of insulin on proliferation of monocytes (1011.4)

Diet macronutrient composition affects insulin action(1). Insulin is essential for metabolic homeostasis in mammals(2). THP‐1 is a human myeloid leukemia cell line(3) which is a suitable model‐system for mimicking human monocytes and macrophages in metabolic inflammation, diabetes and vasculature‐related research(4‐6) . In this study, we used THP‐1 cells to investigate if insulin affect proliferation. Actively proliferating THP‐1 cells were...