Triorganotins inhibit the mitochondrial inner membrane anion channel.

Volume: 266, Issue: 26, Pages: 17250 - 17256
Published: Sep 15, 1991
Abstract
The inner membrane of liver and heart mitochondria possesses an anion uniport pathway, known as the inner membrane anion channel (IMAC). IMAC is inhibited by matrix Mg2+, matrix H+, N,N'-dicyclohexycarbodiimide, mercurials and amphiphilic amines such as propranolol. Most of these agents react with a number of different mitochondrial proteins and, therefore, more selective inhibitors have been sought. In this paper, we report the discovery of a...
Paper Details
Title
Triorganotins inhibit the mitochondrial inner membrane anion channel.
Published Date
Sep 15, 1991
Volume
266
Issue
26
Pages
17250 - 17256
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