Circulating Levels of Betatrophin and Irisin Are Not Associated with Pancreaticβ-Cell Function in Previously Diagnosed Type 2 Diabetes Mellitus Patients

Betatrophin and irisin are two recently identified hormones which may participate in regulating pancreatic β-cell function. However, the associations of these two hormones with β-cell function remain unclear. The present study aims to demonstrate the associations of circulating betatrophin and irisin levels with β-cell function, assessed by the area under the curve (AUC) of C-peptide, and the possible correlation between these two hormones in...