The stability and structure of mixed lipid monolayers and bilayers

Myelinics were prepared by dispersing ovolecithin alone, ovolecithin and retinol, ovolecithin and tocopherol, or ovolecithin and cholesterol in water. Electron microscopic observations of the negatively stained myelinics showed that retinol, tocopherol, and cholesterol decreased (in the order given) the thickness of the hydrophobic regions of the lipid bilayers and increased the mean hydrophilic layer thickness, compared to myelinics of...