The roles of peptidyl-proline isomerases in gene regulation¹This review is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal’s usual peer review process.

The post-translational modification of proteins and enzymes provides a dynamic and reversible means to control protein function and transmit biological signals. While covalent modifications such as phosphorylation and acetylation have drawn much attention, in the past decade the involvement of peptidyl-proline isomerases (PPIs) in signaling and post-translational modification of protein function has become increasingly apparent. Three distinct...