Diet-induced obesity and kidney disease – In search of a susceptible mouse model

Volume: 124, Pages: 65 - 73
Published: May 1, 2016
Abstract
Obesity and metabolic syndrome are independent risk factors for chronic kidney disease, even without diabetes or hyperglycemia. Here, we compare two mouse models that are susceptible to diet-induced obesity: the relatively renal injury resistant C57BL/6J strain and the DBA2/J strain which is more sensitive to renal injury. Our studies focused on characterizing the effects of high fat diet feeding on renal oxidative stress, albuminuria, fibrosis...
Paper Details
Title
Diet-induced obesity and kidney disease – In search of a susceptible mouse model
Published Date
May 1, 2016
Journal
Volume
124
Pages
65 - 73
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