Regulation of the sodium‐activated potassium channel Slack by MAGI‐1

Volume: 29, Issue: S1
Published: Apr 1, 2015
Abstract
The sodium‐activated potassium subunit Slack (Kcnt1) is highly expressed in sensory neurons and contributes to firing accommodation. Previous studies have shown that protein kinase A‐induced internalization of Slack channels contributes to hyperexcitability in DRG neurons. These results suggest that the molecular modulators of Slack channel trafficking could serve as novel therapeutic targets in the treatment of pain. In this study, we probed...
Paper Details
Title
Regulation of the sodium‐activated potassium channel Slack by MAGI‐1
Published Date
Apr 1, 2015
Volume
29
Issue
S1
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