Clinical, genetic and molecular aspects of membranous nephropathy
Published: Jun 28, 2011
Abstract
Membranous Nephropathy (MN) is one of the leading causes of end-stage renal
disease (ESRD). MN is an autoimmune disease in which autoantibodies target
antigens at the level of the glomerular basement membrane. The nature of these
antibodies and the reason why they develop are not fully understood.
One of the strategies towards a better understanding of the disorder is genetic
analysis, of which two approaches have been attempted: linkage...
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