mTOR and its tight regulation for iNKT cell development and effector function

Volume: 68, Issue: 2, Pages: 536 - 545
Published: Dec 1, 2015
Abstract
Invariant NKT (iNKT) cells, which express the invariant Vα14Jα18 TCR that recognizes lipid antigens, have the ability to rapidly respond to agonist stimulation, producing a variety of cytokines that can shape both innate and adaptive immunity. iNKT cells have been implicated in host defense against microbial infection, in anti-tumor immunity, and a multitude of diseases such as allergies, asthma, graft versus host disease, and obesity. Emerging...
Paper Details
Title
mTOR and its tight regulation for iNKT cell development and effector function
Published Date
Dec 1, 2015
Volume
68
Issue
2
Pages
536 - 545
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