A hydrogen tethered inhibitor of matrix metalloproteinases
Published: Jan 1, 2010
Abstract
During wound repair, the balance between matrix metalloproteinases (MMPs) and their natural inhibitors (the TIMPs) is crucial for the normal extra cellular matrix turnover. null However, the over expression of several MMPs including MMP-1, 2, 3, 8, 9 and MMP-10, combined with abnormally high levels of activation or low expression of TIMPs, may contribute to excessive degradation of connective tissue and formation of chronic ulcers. null There...
Paper Details
Title
A hydrogen tethered inhibitor of matrix metalloproteinases
Published Date
Jan 1, 2010
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