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The Journal of Membrane Biology
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1.75
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6155
Papers 6162
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#1Odette Verdejo-Torres (CINVESTAV)H-Index: 3
#2Catalina Flores-Maldonado (CINVESTAV)H-Index: 15
Last.Rubén G. Contreras (CINVESTAV)H-Index: 26
view all 9 authors...
Studies made in the Madin-Darby canine kidney (MDCK) epithelial cell line showed that ouabain regulates cell adhesion and cell-adhesion-related biological processes, such as migration. Here, we demonstrated that 10 nM ouabain accelerates collective cell migration and heals wounds in cultured MDCK cell monolayers. Ouabain-induced acceleration of cell migration depends on activation of the cSrc-ERK1/2 signaling cascade, as it was inhibited by the kinase inhibitors PP2 and PD98059. Activation of th...
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#1Charles R. Sanders (Vandy: Vanderbilt University)H-Index: 40
A subjective account is presented of challenges and excitement of being a postdoctoral trainee in the lab of James H. Prestegard at Yale University in New Haven, Connecticut from 1989 to 1991. This includes accounts of the early development of bicelles and of oriented sample NMR results that contributed to our modern understanding of the properties of the water–lipid interface of disordered phase biological membranes.
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#1Gamaleldin I. Harisa (KSU: King Saud University)H-Index: 10
#2Tarek M. Faris (Al-Azhar University)
Intracellular compartment drug delivery is a promising strategy for the treatment of diseases. By this way, medicines can delivered to particular intracellular compartments. This maximizes the therapeutic efficacy and safety of medicines, particularly of anticancer and antiviral drugs. Intracellular compartment drug delivery is either indirectly by targeting of cell nucleus as central compartment of the cell or directly through the targeting of compartments itself. Drugs or nanoshuttles labeled ...
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The high demand of the fetus for Docosahexaenoic acid, DHA, is satisfied by a concert of several mechanisms that take place in the placental terminal villi. Scarcity of laboratory data makes the detailed description of these mechanisms elusive. Here, the DHA transport across the placenta is modeled as a boundary value problem that accounts for diffusion, reactions with fatty acids binding proteins, FABPs, and metabolic consumption within the Syncytiotrophoblast, ST. For any given DHA fluxes at t...
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#1Kubra Karaosmanoglu Yoneten (Kocaeli University)H-Index: 1
#2Murat Kasap (Kocaeli University)H-Index: 10
Last.Erdal KaraozH-Index: 21
view all 5 authors...
Plasma membrane proteins perform a variety of important tasks in the cells. These tasks can be diverse as carrying nutrients across the plasma membrane, receiving chemical signals from outside the cell, translating them into intracellular action, and anchoring the cell in a particular location. When these crucial roles of plasma membrane proteins are considered, the need for their characterization becomes inevitable. Certain characteristics of plasma membrane proteins such as hydrophobicity, low...
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#2Vladimir L. Zhuravlev (University Hospital Heidelberg)H-Index: 2
Last.Johannes Brachmann (University of Würzburg)H-Index: 40
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Effects of ibutilide, a class III antiarrhythmic drug, on delayed rectifier potassium currents (IK) in freshly isolated guinea pig ventricular myocytes were studied. Experiments were performed using the whole-cell configuration of patch-clamp technique under blockade of L-type calcium currents (Cav1). Ibutilide at concentrations ranging between 10 nM and 100 µM inhibited IKr in dose-dependent manner with a half maximal effective concentration of 2.03 ± 0.74 µM (n = 5–10). The amplitude of tail c...
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#1Odette Verdejo-Torres (CINVESTAV)H-Index: 3
#2Catalina Flores-Maldonado (CINVESTAV)H-Index: 15
Last.Rubén G. Contreras (CINVESTAV)H-Index: 26
view all 9 authors...
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#1Elisabeth Mantil (Carleton University)H-Index: 3
#2Iryna Buznytska (Carleton University)
Last.Tyler J. Avis (Carleton University)H-Index: 19
view all 5 authors...
Fengycins are compounds produced by bacteria of the Bacillus genus with strong antifungal activity. In this work, lipids extracted from fungal and oomycetal molds were used to assess the ability of fengycin to bind and insert into complex membrane models prepared as Langmuir lipid monolayers. In addition, fengycin-induced leakage in liposomes prepared from these complex lipid extracts was also evaluated. Fengycin’s ability to bind and incorporate into these membranes seemed to be mainly related ...
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#1Nikhil Sangith (Anna University)
#2Subramani Kumar (Anna University)H-Index: 2
Last.Krishnan Sankaran (Anna University)H-Index: 19
view all 3 authors...
The unique and ubiquitous bacterial lipoprotein biosynthesis pathway is an attractive new antibiotic target. Crystal structures of its three biosynthetic enzymes have been solved recently. The first enzyme, Phosphatidylglycerol:proLipoprotein diacylglyceryl Transferase (Lgt), which initiates the post-translational modification at the metabolic interface of protein biosynthesis, phospholipid biosynthesis, protein secretion and lipid modification was reported to be a seven-transmembrane helical st...
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Top fields of study
Membrane potential
Chemistry
Membrane
Chromatography
Biochemistry