Molecular Medicine Reports
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#1Zhanjiang Yu (Qiqihar Medical University)
#2Wei Zhang (Qiqihar Medical University)H-Index: 3
Last. Na Wang (Qiqihar Medical University)
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#1Li‑Juan Cao (IMUN: Inner Mongolia University for Nationalities)
#2Hai‑Tang Xie (IMUN: Inner Mongolia University for Nationalities)
Last. Zhuang Shi (IMUN: Inner Mongolia University for Nationalities)
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#1Zhidong Zhou (NCU: Nanchang University)
#2Hejian Li (NCU: Nanchang University)
Last. Jun Luo (NCU: Nanchang University)H-Index: 2
view all 8 authors...
Abnormal microRNA (miRNA) expression has been implicated in spinal cord injury (SCI), but the underlying mechanisms are poorly understood. To observe the effect of electroacupuncture (EA) on miRNA expression profiles in SCI rats and investigate the potential mechanisms involved in this process, Sprague‑Dawley rats were divided into sham, SCI and SCI+EA groups (n=6 each). Basso, Beattie and Bresnahan (BBB) scoring and hematoxylin‑eosin staining of cortical tissues were used to evaluate spinal cor...
#1Sujuan SunH-Index: 3
#2Litao LiH-Index: 2
Last. Hebo Wang
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#1Jin Liu (Nanjing Medical University)H-Index: 1
#2Peng Wu (Nanjing Medical University)H-Index: 4
Last. Zhijian Yang (Nanjing Medical University)H-Index: 23
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Ginkgolide B (GB) is a diterpene lactone found in the leaves of the traditional Chinese medicinal plant Ginkgo that has been shown to have various pharmacological effects. However, the antiapoptotic properties of GB in cardiovascular disease remain poorly understood. The present study aimed to investigate the effect of GB on hydrogen peroxideinduced cell injury in cardiac H9c2 cells, and to further clarify its protective mechanism of action. An in vitro hydrogen peroxidetreated H9c2 cell model w...
#1Dan Ye (ZJU: Zhejiang University)H-Index: 3
#2Guo‑Hua Lou (ZJU: Zhejiang University)
Last. Shen‑Jiang Hu (ZJU: Zhejiang University)H-Index: 1
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Hyperglycemia contributes to the excessive proliferation and migration of vascular smooth muscle cells (VSMC), which are closely associated with atherosclerosis. MicroRNAs (miRNAs/miRs) constitute a novel class of gene regulators, which have important roles in various pathological conditions. The aim of the present study was to identify miRNAs involved in the high glucose (HG)induced VSMC phenotype switch, and to investigate the underlying mechanism. miRNA sequencing and reverse transcriptionqua...
#1Jieshan Lin (Academy of Medical Sciences, United Kingdom)
#2Qingyu Kong (SYSU: Sun Yat-sen University)
Last. Wenxue Hu (Academy of Medical Sciences, United Kingdom)H-Index: 2
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Glucose is the primary osmotic medium used in most peritoneal dialysis (PD) solutions, and longterm exposure to high glucose is a major contributor to peritoneal fibrosis. Our previous study revealed that M2 macrophages participate in the development of PDrelated fibrosis in a rat model. In the present study, the effects of high glucose on peritoneal macrophage polarization in vivo and in vitro were further evaluated. Continuous ambulatory PD (CAPD) patients with an overnight dwell of 1.5 or 2.5...
#1Qing‑Long Tan (Guangzhou University of Chinese Medicine)
#2Chang‑Yuan Zhou (Guangzhou University of Chinese Medicine)
Last. Xing Zeng (Guangzhou University of Chinese Medicine)H-Index: 6
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Bacillus CalmetteGuerin (BCG) is considered to be a successful biotherapy for treating bladder cancer (BCa). However, the underlying mechanisms of BCG have not been completely clarified, to date. The role of macrophages in BCG therapy for BCa has still not been determined in vivo. In the present study, the role and potential mechanism of BCG (0.25, 1.25 and 6.25 microg/mouse; intravenous) immunotherapy for BCa was investigated in a NOD/scid IL2Rg/ (NSI) mouse model by targeting macrophages in vi...
#1Yuan-yuan Zhang (PRC: China Medical University (PRC))H-Index: 1
#2Yu-Lou Tian (PRC: China Medical University (PRC))H-Index: 1
Last. Yang Zhang (PRC: China Medical University (PRC))H-Index: 1
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Periodontal accelerate osteogenesis orthodontics (PAOO) is an extension of described techniques that surgically alter the alveolar bone; however, the specific mechanism underlying the technique is not completely understood. The aim of the present study was to evaluate the roles of microRNA (miR)21 during PAOO. SpragueDawley rats were divided into the following four groups: i) Group tooth movement (TM), underwent TM and were administered normal saline (NS); ii) Group PAOO, underwent PAOO + TM and...
Top fields of study
Molecular biology
Cell cycle
Cancer research
Molecular medicine