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Frontiers in Psychiatry
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#1Rajat M. Thomas (UvA: University of Amsterdam)H-Index: 18
#2Selene Gallo (UvA: University of Amsterdam)
Last. Guido van Wingen (UvA: University of Amsterdam)H-Index: 36
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Resting-state functional magnetic resonance imaging (rs-fMRI) data are 4-Dimensional volumes (3-space + 1-time) that have been posited to reflect the underlying mechanisms of information exchange between brain regions, thus making it an attractive modality to develop diagnostic biomarkers of brain dysfunction. The enormous success of deep learning in computer vision has sparked recent interest in applying deep learning in neuroimaging. But the dimensionality of rs-fMRI data is too high (~20M), m...
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#1Michele Fornaro (University of Naples Federico II)H-Index: 25
#2Andrea Fusco (University of Naples Federico II)H-Index: 2
Last. Andrea de Bartolomeis (University of Naples Federico II)H-Index: 27
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Objective: Treatment-resistant depression (TRD) and treatment-resistant bipolar depression (TRBDe) poses a significant clinical and societal burden, relying on different operational definitions and treatment approaches. The detection of clinical predictors of resistance is elusive, soliciting clinical subtyping of the depressive episodes, which represents the goal of the present study. Methods: A hundred and thirty-one depressed outpatients underwent psychopathological evaluation using major rat...
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#1Diego F Tavares (USP: University of São Paulo)H-Index: 2
#2Carla Garcia Rodrigues dos Santos (USP: University of São Paulo)
Last. Ricardo Alberto Moreno (USP: University of São Paulo)H-Index: 21
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INTRODUCTION: Mixed-specifier mood disorders are probably a different subgroup in terms of response to treatment, socio-demographic parameters, course and family history. Here we describe the rationale and design of a clinical trial aimed to test the efficacy, safety and tolerability of a non-pharmacological treatment known as theta-burst stimulation (TBS) for treating the mixed depressive episodes of both bipolar (I or II), and unipolar depression. METHODS: The study is designed as a randomized...
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#1H.M. Endedijk (UU: Utrecht University)H-Index: 5
#2Stefanie A. Nelemans (UU: Utrecht University)H-Index: 9
Last. C.H. Vinkers (UvA: University of Amsterdam)
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Adolescence is a critical developmental period characterized by heightened levels of depressive and anxiety symptoms. Experiencing chronic or environmental stress, for example as a result of traumatic events or insensitive parenting, increases the risk for depression and anxiety. However, not all adolescents develop depressive or anxiety symptoms following environmental stressors, due to differences in stress resilience. One of the factors involved in stress resilience is enhanced functionality ...
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#2Maeve Connolly (UCC: University College Cork)
Last. Dervla O'Malley (UCC: University College Cork)H-Index: 20
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Tuft cells are rare chemosensory sentinels found in the gut epithelium. When triggered by helminth infection, tuft cells secrete interleukin-25 (IL-25) basolaterally and subsequently evoke an immune response. Irritable bowel syndrome (IBS) is a common and heterogeneous disorder characterised by bowel dysfunction and visceral pain sensitivity. Dysfunctional gut-brain communication and immune activation contribute to the pathophysiology of this disorder. The study aims were to investigate changes ...
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#1Zina-Mary Manjaly (ETH Zurich)H-Index: 2
#2Sandra Iglesias (UZH: University of Zurich)H-Index: 6
Mindfulness Based Cognitive Therapy (MBCT) was developed to combine methods from cognitive behavioral therapy and meditative techniques, with the specific goal of preventing relapse in recurrent depression. While supported by empirical evidence from multiple clinical trials, the cognitive mechanisms behind the effectiveness of MBCT are not well understood in computational (information processing) or biological terms. This article introduces a testable theory about the computational mechanisms be...
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#1Dongying Ji (BNU: Beijing Normal University)
#2Yaping Yue (Henan University)
Burnout in kindergarten teachers is influenced by individual factors, social factors, and organizational factors. Kindergarten organizational climate as an external work resource may cause teacher burnout when it cannot meet their work demands. To explore the mechanisms that underlie the effects of kindergarten organizational climate on teacher burnout, we investigated the mediating effect of work-family conflict (i.e., work interfering with family and family interfering with work) on the relati...
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Psychiatry
Developmental psychology
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