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Veterinary Microbiology
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2.79
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9493
Papers 9418
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#1Jikai Zhang (Harbin Veterinary Research Institute)H-Index: 4
#2Zhijie Li (Harbin Veterinary Research Institute)H-Index: 4
Last. Liandong Qu (Harbin Veterinary Research Institute)H-Index: 1
view all 7 authors...
Abstract Feline viral rhinotracheitis is a prevalent disease among cats caused by feline herpesvirus 1 (FHV-1). microRNAs (miRNAs), which serve as important regulatory factors in the host, participate in the regulation of the host innate immune response to virus infection. However, the roles of miRNAs in the FHV-1 life cycle remain unclear. In this study, we found that a new miRNA, miR-101, could suppress FHV-1 replication. FHV-1 infection upregulated the expression level of miR-101 in a cGAS-de...
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#1Jingwei Song (CAU: China Agricultural University)H-Index: 1
#2Chenxi Wang (CAU: China Agricultural University)H-Index: 4
Last. Mingyang Wang (CAU: China Agricultural University)H-Index: 1
view all 14 authors...
Abstract Influenza virus hemagglutinin (HA) plays an important role in viral antigenicity, replication and host range. However, few amino acid positions in HA were reported to play multiple functions in both viral antigenicity and replication. In the present study, through analyzing the amino acid sequences of H9N2 avian influenza viruses (AIVs) isolated from China, we identified a multi-functional substitution of D200N in HA1 protein. Firstly, the substitution of D200N changed the antigenicity ...
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#2Liang LiH-Index: 2
Last. Juan BaiH-Index: 14
view all 9 authors...
Abstract Cholesterol-25-hydroxylase (CH25 H) is a reticulum-associated membrane protein induced by an important interferon-stimulating gene (ISG) and can significantly inhibit some virus replication. But the effect of CH25H on encephalomyocarditis virus (EMCV) is still not clear. In this study, we found that EMCV infection increases significantly the endogenous CH25H expression in BHK-21 and N2a cells. CH25H and cholesterol catalytic oxidation product 25-hydroxycholesterol (25HC) obviously inhib...
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#1Lovelia L. Mamuad (SNU: Sunchon National University)H-Index: 4
#2Byoung Joo Seo (CBNU: Chonbuk National University)
Last. Yong-Il Cho (SNU: Sunchon National University)H-Index: 2
view all 8 authors...
Abstract This study examined the presence of Treponema in lesions using conventional PCR detection methods and investigated the microbiome by performing high-throughput DNA sequencing. Twenty-nine bovine digital dermatitis (BDD) lesions were collected from 25 dairy farms in South Korea that were tested by PCR amplification using sets of one universal, one genus-specific, and three species specific Treponema PCR primers. Three BDD samples were randomly selected and normal tissue samples were subm...
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#1Nicolas KeckH-Index: 7
Last. Marisa Haenni (University of Lyon)H-Index: 20
view all 8 authors...
Abstract Healthcare-associated infections (HAIs) are often overlooked in veterinary medicine. Serratia marcescens isolates were recovered over a ten-year period from companion animals in a French veterinary hospital. The pets were sampled either for diagnostic purposes or to monitor colonization. A retrospective study showed that 32 S. marcescens isolates were identified as HAI cases and a further 22 cases were associated with colonization of the surgical site. Two S. marcescens lineages were re...
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#1Wenqing Ma (SDNU: Shandong Normal University)
#2Hongmei Wang (SDNU: Shandong Normal University)H-Index: 11
Last. Hongbin He (SDNU: Shandong Normal University)H-Index: 7
view all 3 authors...
Abstract MicroRNAs have emerged as important and versatile modulators of immune responses and participate actively in the regulation of host-pathogen interactions. However, the role of miR-2890 in the host response against viral infection is unclear. In this study, we show that bta-miR-2890 facilitates the production of type I interferon (IFN) and IFN-stimulated genes, and inhibits bovine alphaherpesvirus 1 (BoHV-1) replication. Further research showed that bta-miR-2890 actives the type I IFN si...
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#1Baoyuan LiuH-Index: 6
#2Yiyang ChenH-Index: 4
Last. En-Min ZhouH-Index: 16
view all 10 authors...
Abstract Hepatitis E virus (HEV) is a public health concern because of its zoonotic potential; however, the host species spectrum and the genetic diversity of HEV in many birds are unknown. In the present study, a novel genotype avian HEV was isolated from a bird, silkie fowl, and designated CHN-GS-aHEV (GenBank No. MN562265). The genome of CHN-GS-aHEV was analyzed in comparison with other avian HEVs’ and the pathogenicity in silkie fowl was characterized. The results show that the CHN-GS-aHEV s...
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#1Jihane HamdiH-Index: 1
#2Zineb BoumartH-Index: 2
Last. Mehdi El HarrakH-Index: 9
view all 10 authors...
Abstract Lumpy skin disease (LSD) of cattle is caused by a virus within Capripoxvirus genus. It leads to huge economic losses in addition to trade and animal movement limitation. Vaccination is the only economically feasible way to control this vector borne disease. Only live attenuated vaccines have been used so far and no inactivated vaccine has been developed nor tested in cattle. In this study, we developed an inactivated oily adjuvanted vaccine based on Neethling strain and tested it on cat...
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#1Tiantian WuH-Index: 1
#2Yulong WangH-Index: 1
Last. Hongyu CuiH-Index: 12
view all 14 authors...
Abstract Infectious bursal disease virus (IBDV) is the causative agent of infectious bursal disease (IBD), an important immunosuppressive disease seriously threatening poultry farming worldwide. Since the identification of the classic strain in 1957, variant IBDV, very virulent IBDV, and novel variant IBDV have successively emerged brought severe challenges. Over the years, attenuated, intermediate, and intermediate-plus live vaccines have been developed to control the disease. The coexistence of...
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Abstract In this comparative study, we examine the safety of the sheeppox (SPP) and goatpox (GTP) vaccines and the protective response of these vaccines in cattle against a virulent lumpy skin disease (LSD) field strain. The vaccine safety was tested in rabbits, mice and cattle using ten times recommended dose. In the safety trial, none of the vaccinated animals showed any deviation from physiological norms or fever, inappetence or local/ generalized skin reactions. In the challenge trial, both ...
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