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Psychoneuroendocrinology
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#1Maria A. Karalexi (UoA: National and Kapodistrian University of Athens)H-Index: 9
#2Marios K. Georgakis (UoA: National and Kapodistrian University of Athens)H-Index: 8
Last. Fotios C. Papadopoulos (Uppsala University Hospital)H-Index: 18
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Abstract Background Previous studies have examined whether steroid hormone treatment in transgender individuals may affect cognitive function; yet, their limited power does not allow firm conclusions to be drawn. We leveraged data from to-date literature aiming to explore the effect of gender-affirming hormone administration on cognitive function in transgender individuals. Methods A search strategy of MEDLINE was developed (through June 1, 2019) using the key terms transgender, hormone therapy ...
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Abstract Cardiometabolic diseases are the main contributor of reduced life expectancy in patients with schizophrenia. It is now widely accepted that antipsychotic treatment plays an important role in the development of obesity and its consequences. However, some intrinsic mechanisms need to be taken into consideration. One of these mechanisms might be related to impaired hormonal regulation of appetite in this group of patients. In this narrative review, we aimed to dissect impairments of appeti...
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#1Malgorzata W. Kozusznik (Katholieke Universiteit Leuven)
Last. Martin Euwema (Katholieke Universiteit Leuven)H-Index: 28
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Abstract Hair cortisol concentration (HCC) can be a biomarker of long-term exposure to work stress. However, research shows no consistent associations between HCC and self-reported stress. This may be due to stress being treated as a general category, without distinguishing between specific types of sources of stress, and because of a limited use of more elaborate stress assessment techniques involving intensive longitudinal designs. In this study, we analyze the relationship between perceived s...
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Abstract Introduction Disruptions in homeostatic and hedonic food motivation are proposed to underlie anorexia nervosa (AN) and atypical AN, restrictive eating disorders which commonly onset in puberty. Ghrelin, a neuroprotective hormone that drives hedonic eating is increased in AN and is expressed in the hippocampus. White matter (WM) undergoes significant change during puberty in regions involved in food motivation, particularly WM tracts connected with the hippocampus. The association betwee...
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#1Eirini Flouri (IOE: Institute of Education)H-Index: 31
#2Glyn Lewis (UCL: University College London)H-Index: 94
Last. Marta Francesconi (IOE: Institute of Education)H-Index: 1
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Abstract Background Elevations in inflammatory marker levels have been shown to precede internalising and externalising problems in the general child population. One study has found the reverse, that elevations in inflammatory marker levels in childhood follow internalising and externalising problems. However, the authors did not explore the role of the course of these problems in childhood or adjust for a number of potential confounders including psychosocial stressors and prenatal and perinata...
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#1Mia A. McLeanH-Index: 2
#2Gabrielle SimcockH-Index: 15
Last. Suzanne KingH-Index: 36
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Abstract Background The fetal programming hypothesis suggests that prenatal maternal stress (PNMS) influences aspects of fetal development, such as the Hypothalamic Pituitary Adrenal (HPA) axis, enhancing susceptibility to emotional problems. No study (to our knowledge) has investigated this pathway considering development of preschool anxiety symptoms. Using data from the Queensland Flood study (QF2011), our objective was to determine whether toddler HPA-axis functioning mediated the associatio...
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#1Sheila A. M. Rauch (Emory University)H-Index: 26
#2Anthony P. King (UM: University of Michigan)H-Index: 23
Last. Israel Liberzon (UM: University of Michigan)H-Index: 68
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Abstract PTSD is associated with abnormalities in hypothalamic-pituitary-adrenal (HPA) axis activity. This includes enhanced HPA axis negative feedback, attenuated cortisol awakening response, and attenuated cortisol response to personal trauma script. Whether HPA axis function predicts treatment response or treatment related symptom reduction in PTSD remains unclear. In addition, the relative effects of different treatment modalities (i.e., medication and psychotherapy) on HPA axis is unclear. ...
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Abstract Background Breast cancer survivors with elevated inflammation have a greater risk for cancer recurrence, premature mortality, and comorbid disease development. The psychological stress survivors experience when confronted with a breast cancer diagnosis and cancer treatment can heighten inflammation. Identifying factors that reduce stress and inflammation could lead to improvements in survivors’ long-term health. Accordingly, this study examined the health-enhancing effects of romantic r...
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#1Magdalena Sandner (University of Mainz)H-Index: 1
#2Giannis Lois (University of Mainz)H-Index: 4
Last. Michèle Wessa (University of Mainz)H-Index: 33
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Abstract Identifying individual differences in stress reactivity is of particular interest in the context of stress-related disorders and resilience. Previous studies already identified several factors mediating the individual stress response of the hypothalamus–pituitary–adrenal axis (HPA). However, the impact of long-term HPA axis activity on acute stress reactivity remains inconclusive. To investigate associations between long-term HPA axis variation and individual acute stress reactivity, we...
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#1Dora BaloghH-Index: 3
#2Ágnes MolnárH-Index: 22
Last. Andrea FeketeH-Index: 26
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Abstract The incidence of depression doubles in diabetic patients and is associated with poor outcomes. Studies indicate that renin-angiotensin-aldosterone system inhibitors (RAASi) might relieve depression, however the mechanism of action is not well understood. We recently showed that angiotensin receptor blockers have antidepressant effects in experimental diabetes comorbid depression. Here we investigated whether all types of RAASi exhibit antidepressant and neuroprotective properties. Diabe...
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Endocrinology
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Hydrocortisone
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Diabetes mellitus
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