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Practical Neurology
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Published on 2019in Practical Neurology
Andrew J. Lees129
Estimated H-index: 129
(UCL: University College London)
Know how to listen and you will profit even from those who talk badly. Plutarch Listening in medicine is only of value when it is combined with an ability to decipher the patient9s utterances and gestures and act upon them
Published on 2019in Practical Neurology
Dearbhla Kelly3
Estimated H-index: 3
,
Peter M. Rothwell106
Estimated H-index: 106
Published on Sep 18, 2019in Practical Neurology
Rui Esteves Araujo15
Estimated H-index: 15
,
Anouke van Rumund4
Estimated H-index: 4
(Radboud University Nijmegen),
Bastiaan R. Bloem73
Estimated H-index: 73
(Radboud University Nijmegen)
The diagnosis of Parkinson’s disease (PD) is primarily a clinical exercise.1 Structural imaging is not recommended in cases with a typical presentation, and should remain reserved for those patients where there is reasonable doubt about the clinically based diagnosis.2 This is not uncommon: even in tertiary specialised centres, up to 25% of patients initially diagnosed with PD are reclassified at follow-up.3 Triggers to reconsider the diagnosis include presence of absolute exclusion criteria (su...
Published on Sep 18, 2019in Practical Neurology
Lou Wiblin (RVI: Royal Victoria Infirmary), Dipayan Mitra4
Estimated H-index: 4
(RVI: Royal Victoria Infirmary),
Naomi Warren1
Estimated H-index: 1
(RVI: Royal Victoria Infirmary)
A 78-year-old woman presented with features of bilateral, asymmetric Parkinsonism for 1 year, with prominent difficulties with continence, swallowing and apathy. Brain imaging showed evidence of chronic venous sinus thrombosis with dilated serpiginous vessels over the brain surface in keeping with a dural arteriovenous fistula, together with high T2 signal on MRI in the basal ganglia. Having responded only modestly to levodopa, she received 6 months of anticoagulation followed by embolisation of...
Published on Sep 13, 2019in Practical Neurology
David Ledingham2
Estimated H-index: 2
(James Cook University Hospital),
Michael Plant1
Estimated H-index: 1
(James Cook University Hospital)
+ 1 AuthorsBhimanagouda Patil (James Cook University Hospital)
Cytotoxic agents such as cyclophosphamide are infrequently used in neurological practice. When they are, it is commonly in critically ill patients or in those with refractory inflammatory disorders. Cyclophosphamide in particular has a well-recognised negative impact on both female and male long-term fertility. This article summarises the data with regards the impact of cytotoxics on long-term fertility and describes the current options to preserve fertility in these patients. We hope this will ...
Published on Sep 4, 2019in Practical Neurology
Hugh S. Markus91
Estimated H-index: 91
(University of Cambridge)
Stroke is a syndrome caused by many different disease mechanisms rather than being a single disease. It is important to identify the underlying mechanism accurately in individual patients in order to choose the best treatment approach. This article provides practical tips to diagnose the underlying subtype of stroke, and in particular discusses non-lacunar pathologies that can present with a clinical lacunar syndrome. It also reviews the recent advances in recurrent stroke prevention, including ...
Published on Aug 29, 2019in Practical Neurology
Andrew Lee , Leslie R Bridges + 3 AuthorsClare M Galtrey3
Estimated H-index: 3
The incidence of Epstein–Barr virus (EBV)associated lymphoproliferative disorders has increased with greater use of immunomodulatory therapies. We present a woman who developed subacute cognitive decline and unilateral weakness while taking long-term mycophenolate mofetil for granulomatosis with polyangiitis; her postmortem brain histopathology confirmed an EBV-driven lymphoproliferative disorder. Clinicians must have a high index of suspicion for EBV-driven lymphoma in people taking long-term i...
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