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#1Kevin P. Fennelly (NIH: National Institutes of Health)H-Index: 6
#2Carlos Acuña-Villaorduña (BU: Boston University)H-Index: 7
Last.Donald K. Milton (UMD: University of Maryland, College Park)H-Index: 45
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Abstract Pulmonary infections are important causes of global morbidity and mortality, but diagnostics are often limited by the ability to collect specimens easily, safely and in a cost-effective manner. We review recent advances in the collection of infectious aerosols from patients with tuberculosis and with influenza. Although this research has been focused on assessing the infectious potential of such patients, we propose that these methods have the potential to lead to the use of patient-gen...
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#1Grant E. MacKinnon (Vandy: Vanderbilt University)
#2Evan L. Brittain (VUMC: Vanderbilt University Medical Center)H-Index: 16
Abstract Mobile health (mHealth) technologies are modernizing medicine by affording greater patient engagement, monitoring, outreach, and healthcare delivery. The cardiopulmonary fields have led the integration of mHealth into clinical practice and research. mHealth technologies in these areas include smartphone applications, wearable devices, and hand-held devices, among others, and provide real-time monitoring of numerous important physiologic measurements and other key parameters. Use of mHea...
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#1John S. Kim (UVA: University of Virginia)
#2Michaela R. Anderson (CUMC: Columbia University Medical Center)H-Index: 2
Last.Jon T. Giles (CUMC: Columbia University Medical Center)H-Index: 2
view all 12 authors...
Abstract Background Adipokines have inflammatory and fibrotic properties that may be critical in interstitial lung disease (ILD). We examined associations of serum adipokine levels with computed tomography (CT)-based measures of subclinical ILD and lung function among community-dwelling adults. Methods A subset of the original Multi-Ethnic Study of Atherosclerosis cohort (n=1,968) had adiponectin, leptin, and resistin measured during follow-up visits (2002-2005). We used regression models to exa...
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#1Nathan Schoettler (U of C: University of Chicago)H-Index: 4
#2Mary E. Strek (U of C: University of Chicago)H-Index: 21
Abstract This review focuses on recent clinical and translational discoveries in severe and uncontrolled asthma that now enable phenotyping and personalized therapies in these patients. While asthma is common in both children and adults and typically responds to standard therapies, a subset of individuals with asthma experience severe and/or persistent symptoms despite appropriate therapies. Airflow obstruction leading to frequent symptoms requiring higher levels of controller therapy is the car...
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#1M. CorralH-Index: 4
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#1Kelly M. ChinH-Index: 19
#2Nick H. KimH-Index: 24
Last.Richard N. ChannickH-Index: 45
view all 10 authors...
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#1Scott H. Twaddell ('JHCH': John Hunter Hospital)H-Index: 2
#2Katherine J. BainesH-Index: 25
Last.Peter G. Gibson ('JHCH': John Hunter Hospital)H-Index: 83
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Neutrophil extracellular traps (NETs) are extrusions of intracellular DNA and attached granular material that enable bacterial killing. NETs are increasingly recognized for their role in the pathogenesis of respiratory disease. NETs are composed of a complex mix of intracellularly derived material that neutrophils organize within the cytoplasm and then expel in a nondirected manner in the vicinity of invading organisms. Combined, these trap and destroy multiple genera of microbes including bacte...
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