Autonomic Neuroscience: Basic and Clinical
Papers 3621
1 page of 363 pages (3,621 results)
#1Johanna Stenqvist (University of Gothenburg)H-Index: 2
#2Patrik Aronsson (University of Gothenburg)H-Index: 8
Last. Gunnar Tobin (University of Gothenburg)H-Index: 18
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Abstract Mechanical stretch of the urothelium induces the release of ATP that activates bladder afferent nerves. In the rat urinary bladder, ATP is also a contractile co-transmitter in the parasympathetic innervation. In isolated preparations, ATP evokes a urothelial release of acetylcholine that substantially contributes to ATP-evoked contractile responses. Currently we aimed to further examine the interactions of ATP and acetylcholine in the rat urinary bladder in two in vivo models. In the wh...
Abstract Scorpion envenomation is a public health problem in tropical and subtropical areas. In Brazil, Tityus serrulatus is the biggest cause of accidents with venomous animals. Tityus serrulatus venom causes symptoms related to a great activation of the autonomic system attributed to a massive release of sympathetic and parasympathetic mediators. This effect is attributed to the presence of toxins acting in Na+ and K+ ion channels, leading to an increase in cell excitability. Although gastroin...
#1J. Wink (LUMC: Leiden University Medical Center)
#2R. van Delft (LUMC: Leiden University Medical Center)
Last. Monique R.M. Jongbloed (LUMC: Leiden University Medical Center)H-Index: 25
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Abstract Background Cardiac sympathetic blockade is a therapeutic approach for arrhythmias and heart failure and may be a beneficial effect of high thoracic epidural anesthesia. These treatments require detailed knowledge of the spatial location and distribution of cardiac autonomic nerves, however, there are controversies on this subject in humans. Objective To provide a systematic overview of current knowledge on human anatomy of the cardiac autonomic nervous system. Results In contrast to the...
#1Claude Julien (UCBL: Claude Bernard University Lyon 1)H-Index: 24
#2Bruno Chapuis (UCBL: Claude Bernard University Lyon 1)H-Index: 9
Last. Christian Barrès (UCBL: Claude Bernard University Lyon 1)H-Index: 22
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Abstract The relation between vascular sympathetic tone and the amplitude of arterial pressure (AP) Mayer waves was examined by analyzing 60-min recordings of AP and renal sympathetic nerve activity (RSNA) obtained in conscious rats before and after lipopolysaccharide administration, which results in strong sympathoexcitation. Mayer waves completely disappeared together with accompanying oscillations of RSNA. Meanwhile, the gain of the sympathetic baroreceptor reflex was increased, thus suggesti...
#1Gokcen Guvenc-Bayram (Uludağ University)
#1Gokcen Guvenc (Uludağ University)
Last. Figen Ersoy (Uludağ University)
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Abstract Nesfatin-1 is a multifunctional neuropeptide having crucial autonomic roles. It is well known that nesfatin-1 collaborates with other central neuromodulatory systems, such as central corticotropin-releasing hormone, melanocortin, oxytocin, and cholinergic systems to show its autonomic effects. Central arachidonic acid cascade plays an important role to provide the homeostasis by exhibiting similar autonomic effects to nesfatin-1. Based on these similarities, the current study was design...
#1Adina E. Draghici (Harvard University)H-Index: 4
#2J. Andrew Taylor (Harvard University)H-Index: 36
Abstract Spinal cord injury (SCI) leads to autonomic nervous system damage, resulting in loss of sympathetic control to the vasculature and the heart proportional to injury level. Given maintained cardiac parasympathetic control, we hypothesized that SCI demonstrates a compensatory, higher baroreflex gain compared to able-bodied that relates to injury level (neurological and/or sensory). We compared baroreflex gain (average and across 10–20, 20–30, and 30–40 mmHg input stimuli) derived from neck...
#1Fernanda Ribeiro Marins (UFMG: Universidade Federal de Minas Gerais)H-Index: 5
#2Marcelo Limborço-Filho (UFMG: Universidade Federal de Minas Gerais)H-Index: 4
Last. Marco Antônio Peliky Fontes (UFMG: Universidade Federal de Minas Gerais)H-Index: 25
view all 9 authors...
Abstract Damage to the insular cortex (IC) results in serious cardiovascular consequences and evidence indicates that the characteristics are lateralized. However, a study comparing the effects of focal experimental hemorrhage between IC sides was never performed. We compared the cardiovascular, autonomic and cardiac changes produced by focal experimental hemorrhage (ICH) into the left (L) or right (R) IC. Wistar rats were submitted to microinjection of autologous blood (ICH) or saline (n = 6 ea...
#1Selena R Pasadyn (Cleveland Clinic Lerner College of Medicine)H-Index: 1
#2Christine B. Warren (Cleveland Clinic Lerner College of Medicine)H-Index: 3
Last. Robert Wilson (Cleveland Clinic Lerner College of Medicine)H-Index: 2
view all 3 authors...
Abstract Purpose POTS patients undergo labial salivary gland biopsies (LSGB) for histologic confirmation of Sjogren's syndrome (SS). Predictive features of positive results are unknown. Methods 161 POTS patients underwent LSGB. Their charts were reviewed for antibody and diagnostic testing results. Results Only 11% (17/161) of POTS patients were SS positive. There were more positive ANA antibodies in those with positive LSGB (65% v 28%, p = .0026). Positive skin nerve biopsy for small fiber neur...
#1Johanna Stenqvist (University of Gothenburg)H-Index: 2
#2Thomas Carlsson (University of Gothenburg)H-Index: 7
Last. Patrik Aronsson (University of Gothenburg)H-Index: 8
view all 4 authors...
Abstract While acetylcholine is regarded to be the main directly contractile transmitter substance in the urinary bladder, interactions with other transmitters likely occur. Presently, the interplay between purinergic and cholinergic signalling was investigated to unravel the involvement of the urothelium and efferent neurons in the functionally important purinergically evoked release of acetylcholine in vitro. Functional characterization of receptor subtypes involved in this interplay was also ...
#1Carolyn J. Fisher (Cleveland Clinic)H-Index: 1
#2Irene L. Katzan (Cleveland Clinic)H-Index: 29
Last. Robert Wilson (Cleveland Clinic)H-Index: 2
view all 6 authors...
Abstract Psychological symptoms are frequently reported in patients with Postural Orthostatic Tachycardia Syndrome (POTS); however, the nature of these symptoms is not well understood. The current study described baseline psychological symptoms in patients with POTS, and examined associations between psychological and self-report autonomic symptoms. Participants reported mild anxiety symptoms, moderate depressive symptoms, severe somatization, and elevated anxiety sensitivity. Depressive symptom...
Top fields of study
Autonomic nervous system
Heart rate
Diabetes mellitus