Frontiers in Neural Circuits
Papers 1079
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#1Mónica Folgueira (University of A Coruña)H-Index: 11
#2Selva Riva-Mendoza (University of A Coruña)
Last. Julián Yáñez (University of A Coruña)H-Index: 21
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This study describes the cytoarchitecture of the torus longitudinalis (TL) in adult zebrafish by using light and electron microscopy, as well as its main connections as revealed by DiI tract tracing. In addition, by using high resolution confocal imaging followed by digital tracing, we describe the morphology of tectal pyramidal cells (type I cells) that are GFP positive in the transgenic line Tg(1.4dlx5a-dlx6a:GFP)ot1. The TL consists of numerous small and medium-sized neurons located in a long...
#1Khuong H. Nguyen (OU: University of Oklahoma)
#2Thomas E. Scheurich (OU: University of Oklahoma)
Last. Ari Berkowitz (OU: University of Oklahoma)H-Index: 17
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The central nervous system may simplify control of limb movements by activating certain combinations of muscles together, i.e., muscle synergies. Little is known, however, about the spinal cord interneurons that activate muscle synergies by exciting sets of motoneurons for different muscles. The turtle spinal cord, even without brain inputs and movement-related sensory feedback, can generate the patterns of motoneuron activity underlying forward swimming, three forms of scratching, and limb with...
#1Florian SchöberlH-Index: 7
#2Andreas ZwergalH-Index: 20
Last. Thomas BrandtH-Index: 83
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#1Masaru TakabatakeH-Index: 4
#1Masaru Takabatake (YCU: Yokohama City University)
Last. Yukio SasakiH-Index: 16
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Fragile X mental retardation protein (FMRP) is an RNA binding protein that regulates local translation in dendrites and spines for synaptic plasticity. In axons, FMRP is implicated in axonal extension and axon guidance. We previously demonstrated that FMRP is involved in growth cone collapse translation-dependently in response to Semaphorin-3A (Sema3A), a repulsive axon guidance factor. In the case of attractive axon guidance factors, RNA binding proteins, such as zipcode-binding protein 1 (ZBP1...
#1L. Wang (CAS: Chinese Academy of Sciences)H-Index: 84
#2Zhijian Zhang (CAS: Chinese Academy of Sciences)H-Index: 5
Last. Fuqiang XuH-Index: 21
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The piriform cortex (PC) is a key brain area involved in both processing and coding of olfactory information. It is implicated in various brain disorders, such as epilepsy, Alzheimer’s disease and autism. The PC consists of the anterior (APC) and posterior (PPC) parts, which are different anatomically and functionally. However, the direct input networks to specific neuronal populations within the APC and PPC remain poorly understood. Here, we mapped the whole-brain direct inputs to the two major...
2 CitationsSource
#2Hysell V. Oviedo (The Graduate Center, CUNY)H-Index: 6
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The circuits responsible for social communication are some of the most important and least understood in the brain. Human studies have made great progress in advancing our understanding of the global computations required for processing speech, and animal models offer the opportunity to discover evolutionarily conserved mechanisms for decoding these signals. In this review we describe some of the most well-established speech decoding computations from human studies and describe animal studies de...
Electrical kindling, repeated brain stimulation eventually resulting in seizures, is widely used as an animal model of epileptogenesis and epilepsy. However, the stimulation electrode used for electric kindling targets unknown neuronal populations and may introduce tissue damage and inflammation. Optogenetics can be used to circumvent these shortcomings by permitting millisecond control of activity in genetically defined neurons without gross injury or inflammation. Here we describe an easy step...
#1Ido MaorH-Index: 2
#2Ravid Shwartz-Ziv (HUJI: Hebrew University of Jerusalem)H-Index: 1
Last. Adi MizrahiH-Index: 18
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Associative learning of pure tones is known to cause tonotopic map expansion in the auditory cortex (ACx), but the function this plasticity sub-serves is unclear. We developed an automated training platform called the ‘Educage’, which was used to train mice on a go/no-go auditory discrimination task to their perceptual limits, for difficult discriminations among pure tones or natural sounds. Spiking responses of excitatory and inhibitory parvalbumin (PV+) L2/3 neurons in mouse ACx revealed learn...
The unique combination of small size, translucency, and powerful genetic tools makes larval zebrafish a uniquely useful vertebrate system to investigate normal and pathological brain structure and function. While functional connectivity can now be assessed (via fluorescent calcium or voltage reporters) at the whole-brain scale, it remains challenging to systematically determine structural connections and identify connectivity changes during development or disease. To address this, we developed T...
Top fields of study
Inhibitory postsynaptic potential
Sensory system