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Respiratory Medicine
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#1El Hassane Ouaalaya (French Institute of Health and Medical Research)
#2L. FalqueH-Index: 1
Last. Mathieu Molimard (French Institute of Health and Medical Research)H-Index: 40
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Abstract Introduction Exacerbations are key events in the natural history of COPD, but our understanding of their longitudinal determinants remains unclear. We used data from a large observational study to test the hypothesis that vaccination status and comorbidities could be associated with the occurrence of exacerbations profile. Methods Diagnosed COPD patients have been included by their pulmonologists, with up to 3 years of follow-up. Data were analyzed using the KmL method designed to clust...
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#1E. Zamarron (Hospital Universitario La Paz)
#2David Romero (Hospital Universitario La Paz)H-Index: 6
Last. J. Dominguez-Ortega (Hospital Universitario La Paz)
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Abstract Background It is essential to recognize and treat findings that can simulate or worsen symptoms to improve asthma control and thereby to reduce costs. Guidelines highlight a paranasal (PS) and chest computed tomography (CT) scan as a tool for disease evaluation and, although they suggest its indication in patients whom presentation is atypical, there are not well-defined criteria. Objectives To describe the most common findings in the PS and chest CT in severe asthma patients and to ana...
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#1Miia Aro (UTU: University of Turku)
#2Tarja Saaresranta (UTU: University of Turku)H-Index: 21
Last. Ulla Anttalainen (UTU: University of Turku)H-Index: 10
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Abstract Background Treating sleep disordered breathing (SDB) with nasal continuous positive airway pressure (CPAP) may reduce mortality, but the studies on the effect on medication use are few. Women tend to have more mild sleep apnoea and partial airway obstruction and are therefore expected to have less co-morbidity. The purpose of this study was to evaluate the effect of CPAP therapy on medication use in women as overall medication, and in different subcategories of diseases, and to evaluate...
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#1Hyungseok KangH-Index: 4
#2Kyung-Wook JoH-Index: 10
Last. Tae Sun ShimH-Index: 33
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Abstract Purpose The Korea Centers for Disease Control & Prevention has implemented a review process for the approval of new drugs used to treat patients with multidrug-resistant tuberculosis (MDR-TB) since September 2016. Therefore, this study aimed to evaluate the efficacy and safety of these new drugs bedaquiline (Bdq) and delamanid (Dlm). Methods A total of 318 patients with MDR-TB were reviewed by the committee from September 2016 to February 2018; 282 (88.7%) of them were treated with the ...
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Abstract Introduction COPD exacerbation phenotypes have been defined in research populations by predominantly infective or inflammatory aetiology. We sought to characterise this in patients admitted to our centre. Materials and methods Case-notes of consecutive patients discharged alive after treatment for acute COPD exacerbations between December 2012 and January 2017 were analysed. Data were collected on treatment, length of stay, C-reactive protein (CRP), eosinophil count and bacterial sputum...
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#1Ahmad Zaheen (U of T: University of Toronto)H-Index: 8
#2Takashi HiramaH-Index: 6
Last. Theodore K. Marras (U of T: University of Toronto)H-Index: 20
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Abstract Mycobacterium xenopi is associated with the highest mortality among pulmonary nontuberculous mycobacterial (NTM) infections, but whether this is due to the infection or other factors is unclear. There is little information regarding outcomes among patients infected with M. xenopi versus other NTM species. We conducted a retrospective matched cohort study comparing M. xenopi pulmonary disease (Mx-PD) to M. avium complex (MAC)-PD. Patients were matched by sex, age, radiologic subtype, and...
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#1M. C. J. van ThorH-Index: 1
#2L. ten KloosterH-Index: 1
Last. Martijn C. PostH-Index: 24
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Abstract Background Macitentan treatment for chronic thromboembolic pulmonary hypertension (CTEPH) in the routine clinical setting is increasing. However, ‘real world’ macitentan experience is scarce and is needed to differentiate from controlled clinical trial settings. Objective We describe our outcomes and clinical ‘real world’ experience of macitentan mono- and combination therapy with riociguat or sildenafil in CTEPH. Methods We included all consecutive CTEPH patients, either non-operated o...
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#1Arzu Ari (Texas State University)H-Index: 2
The COVID-19, the disease caused by a novel coronavirus and named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly across the globe. It has caused outbreaks of illness due to person-to-person transmission of the virus mainly via close contacts and droplets produced by an infected person's cough or sneeze. Exhaled droplets from infected patients with COVID-19 can be inhaled into the lungs and leads to respiratory illness such as pneumonia and acute respiratory dist...
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