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Biointerphases
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#1Norsyahidah Mohd Hidzir (UQ: University of Queensland)H-Index: 4
#2A. Anitha (UQ: University of Queensland)H-Index: 15
Last. Lisbeth Grøndahl (UQ: University of Queensland)H-Index: 24
view all 6 authors...
Protein adsorption to biomaterial surfaces is important for the function of such materials with anchorage-dependent cell adhesion requiring the presence of adsorbed proteins. The current study evaluated five solid surfaces with poly(acrylic acid) (PAA) grafted from the surface of a poly(tetrafluoroethylene) membrane with respect to the adsorption of serum albumin (SA), lactoferrin (Lf), and lysozyme (Lys) from a phosphate buffer and NaCl solution or water for specific combinations. With the use ...
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#1Wren Gregory (Clemson University)H-Index: 2
#2Bipin Sharma (Clemson University)
Last. Ramakrishna Podila (Clemson University)H-Index: 31
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Amyloid fibrillation is known to contribute in a variety of diseases including neurodegenerative disorders (e.g., Alzheimer's and Parkinson's disease) and type II diabetes. The inhibition of fibrillation has been suggested as a possible therapeutic strategy to prevent neuronal and pancreatic β-cell death associated with amyloid diseases. To this end, strong hydrophobic and π-π interactions between proteins and nanomaterials at the nanobio interface could be used to mitigate the stacking of amylo...
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#1Jequil S. R. Hartz (UMaine: University of Maine)
#2Nuri W. Emanetoglu (UMaine: University of Maine)H-Index: 1
Last. John F. Vetelino (UMaine: University of Maine)H-Index: 26
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The most common bulk acoustic wave device used in biosensing applications is the quartz crystal microbalance (QCM), in which a resonant pure shear acoustic wave is excited via electrodes on both major faces of a thin AT-cut quartz plate. For biosensing, the QCM is used to detect the capture of a target by a target-capture film. The sensitivity of the QCM is typically based solely on the detection of mechanical property changes, as electrical property change detection is limited by the electrode ...
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#1Domenik Prozeller (MPG: Max Planck Society)H-Index: 2
#2Christine Rosenauer (MPG: Max Planck Society)H-Index: 11
Last. Katharina Landfester (MPG: Max Planck Society)H-Index: 73
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The overall success of nanocarriers in biomedical applications depends on their interaction with different proteins in blood. Immunoglobulins as a major protein class of the blood proteome may considerably influence the identity of the nanocarriers in blood. However, there is a lack of knowledge about the specific details of the interaction mechanism between different immunoglobulins and nanocarriers. Therefore, the authors have investigated the interaction of different immunoglobulin classes—na...
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#1Hyun Kyong Shon (KRISS: Korea Research Institute of Standards and Science)H-Index: 16
#2Jin Gyeong Son (KRISS: Korea Research Institute of Standards and Science)H-Index: 1
Last. Tae Geol Lee (KRISS: Korea Research Institute of Standards and Science)H-Index: 25
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Nanoparticles (NPs) are substances between 1 and 100 nm in size. They have been the subject of numerous studies because of their potential applications in a wide range of fields such as cosmetics, electronics, medicine, and food. For biological applications of nanoparticles, they are usually coated with a substance capable of preventing agglomeration of the nanoparticles and nonspecific binding and exhibiting water-solubility characteristics with specific immobilized (bio)molecules. In order to ...
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#1Todd E. Alexander (WPI: Worcester Polytechnic Institute)H-Index: 1
#2Ian M. Smith (WPI: Worcester Polytechnic Institute)
Last. Terri A. Camesano (WPI: Worcester Polytechnic Institute)H-Index: 32
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Antimicrobial peptides (AMPs) are attractive as biomaterial coatings because they have broad spectrum activity against different microbes, with a low likelihood of incurring antimicrobial resistance. Direct action against the bacterial membrane is the most common mechanism of action (MOA) of AMPs, with specific MOAs dependent on membrane composition, peptide concentration, and environmental factors that include temperature. Chrysophsin-1 (CHY1) is a broad spectrum salt-tolerant AMP that is deriv...
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#1Yurij Stetsyshyn (Lviv Polytechnic)H-Index: 8
#2Joanna Raczkowska (Jagiellonian University)H-Index: 16
Last. Mykola SharanH-Index: 1
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: In the present work, three types of grafted brush coatings [P4VP, POEGMA246, and P(4VP-co-POEGMA246)] were successfully fabricated using graft polymerization of monomers "from the surface." The composition, thickness, and morphology of the grafted brush coatings were analyzed by TOF-SIMS, ellipsometry, and AFM, respectively. The chemical nature of the polymer surface plays a crucial role in the growth and development of the cow granulosa cells and, therefore, also oocyte-cumulus complexes. In ...
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#1Christine Kern (University of Giessen)
#2Seemun Ray (University of Giessen)H-Index: 7
Last. Marcus Rohnke (University of Giessen)H-Index: 18
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: The present work focuses on the application of time-of-flight secondary ion mass spectrometry (ToF-SIMS) in osteoporotic bone research. In order to demonstrate the benefit, the authors present concrete application examples of ToF-SIMS in three different areas of bone research. ToF-SIMS as a mass spectrometric imaging technique allows simultaneous visualization of mineralized and nonmineralized bone tissue as well as implanted biomaterials and bone implant interphases. In the first example, the...
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#1Serena Danti (MIT: Massachusetts Institute of Technology)H-Index: 16
#2Bahareh Azimi (MIT: Massachusetts Institute of Technology)H-Index: 1
Last. Giovanna DonnarummaH-Index: 22
view all 14 authors...
: Sensorineural hearing loss (SNHL) affects the inner ear compartment and can be caused by different factors. Usually, the lack, death, or malfunction of sensory cells deputed to transduction of mechanic-into-electric signals leads to SNHL. To date, the therapeutic option for patients impaired by severe or profound SNHL is the cochlear implant (CI), a high-tech electronic device replacing the entire cochlear function. Piezoelectric materials have catalyzed attention to stimulate the auditory neu...
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