Experimental and Clinical Endocrinology & Diabetes
Papers 6425
1 page of 643 pages (6,425 results)
#1Mao Ouyang (CSU: Central South University)
#2Tao Qin (CSU: Central South University)
Last. Qin Guo (CSU: Central South University)
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OBJECTIVE: High-fat diet (HFD) increases the risk of inflammatory reaction and acute arterial thrombosis. Celastrol has been confirmed to regulate inflammatory cytokine levels in atherosclerotic animal models. However, the anti-thrombotic effects of celastrol have remained to be fully demonstrated. The present study was performed to investigate the beneficial effect of celastrol in HFD-induced inflammatory reaction and thrombosis in apolipoprotein (apo)E(-/-) mice. MATERIALS AND METHODS: Thrombo...
#1Laura Dauben (HHU: University of Düsseldorf)
#2Ks Weber (HHU: University of Düsseldorf)H-Index: 5
Last. Karsten MüssigH-Index: 13
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Background Children with migration background and from low socio-economic status are at higher risk for overweight. To determine appropriate media channels to possibly reach children with targeted health information, it has to be considered that the media and information behavior of children has changed during the last decades. Objective We examined the media and information behavior of children in low socio-economic districts, focusing on those with migration background. Methods Fourteen 3rd gr...
#1Sebastian Hörber (University of Tübingen)H-Index: 3
#2Angela Lehn-Stefan (University of Tübingen)H-Index: 7
Last. Elko Randrianarisoa (University of Tübingen)H-Index: 6
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Background Type 2 diabetes mellitus (T2DM) promotes the development of atherosclerosis and is a major risk factor for cardiovascular disease. High-sensitivity cardiac troponin I (hs-cTnI) assays fundamentally improved the diagnosis of myocardial injury and even enable the prediction of future cardiovascular events in the general population. However, data about the association of hs-cTnI with cardiovascular risk factors and carotid intima media thickness (cIMT) as a marker of atherosclerosis are ...
#1Berta Carvalho (University of Porto)H-Index: 3
#1Bruno Carvalho (University of Porto)H-Index: 7
Last. Filipa Carvalho (University of Porto)H-Index: 21
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Congenital Adrenal Hyperplasia is a group of genetic autosomal recessive disorders that affects adrenal steroidogenesis in the adrenal cortex. One of the most common defects associated with Congenital Adrenal Hyperplasia is the deficiency of 21-hydroxylase enzyme, responsible for the conversion of 17-hydroxyprogesterone to 11-deoxycortisol and progesterone to deoxycorticosterone. The impairment of cortisol and aldosterone production is directly related to the clinical form of the disease that ra...
#1Fei Sun ('SMMU': Second Military Medical University)H-Index: 1
#2Wen-Hua DuH-Index: 6
Last. Guan-Qi GaoH-Index: 10
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Background Neonatal diabetes mellitus is likely caused by monogenic mutations, several of which have been identified. INS mutations have a broad spectrum of clinical presentations, ranging from severe neonatal onset to mild adult onset, which suggests that the products of different mutant INS alleles behave differently and utilize distinct mechanisms to induce diabetes. In this study, a neonatal diabetes mellitus patient’s INS gene was sequenced, and functional experiments were conducted. Method...
Purpose To assess quality of life, glycemic control, and safety/tolerability associated with liraglutide versus insulin initiation in patients with type 2 diabetes in Germany. Methods Liraglutide/insulin-naive adults with type 2 diabetes and inadequate glycemic control despite using oral antidiabetic medication were assigned to liraglutide (≤1.8 mg daily; n=878) or any insulin (n=382) according to the treating physician’s decision and followed for 52 weeks. The primary objective was to evaluate ...
1 CitationsSource
#1Ya-Di Wang (University of South China)H-Index: 2
#2Jiao-Yang Li (University of South China)H-Index: 1
Last. Xin-Hua Xiao (University of South China)H-Index: 9
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Fatty acids induced hepatic inflammation plays an important role in nonalcoholic fatty liver disease (NAFLD) pathogenesis. Hydrogen sulfide (H2S), an endogenous gasotransmitter, has been established to possess potent anti-inflammation in various human organs. However, the anti-inflammation property of H2S in the fatty liver is still needed to further elucidate. Hence, this study aimed to investigate whether exogenous H2S can protect hepatocytes against inflammation induced by palmitic acid (PA). ...
#1Jing Zhao (SDU: Shandong University)H-Index: 1
#2Xiaoyan Liu (SDU: Shandong University)H-Index: 1
Last. Wenhua Zhang (SDU: Shandong University)H-Index: 1
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Objective This study was to analyze the efficacy of metformin intervention in preventing gestational diabetes mellitus (GDM). Methods A systematic review and meta-analysis of clinical trials or observational studies of metformin intervention in preventing symptoms of GDM during pregnancy were performed. Medline, Embase, and Cochrane Library were searched through to now. The main evaluated primary outcomes were incident of GDM, miscarriage, preterm delivery, and neonatal mortality. The evaluated ...
3 CitationsSource
#1Marwa Hassan Muhammad (Banha University)H-Index: 1
#2Noha I. Hussien (Banha University)H-Index: 3
Last. Sania K. Elwia (Banha University)
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Background & Aim Dyslipidaemia is highly prevalent among postmenopausal women and its management represents a keystone in the prevention of the worldwide increase in cardiovascular morbidity and mortality. Therapy choices for menopause-associated dyslipidaemia are limited and a matter of debate. So, it becomes prudent to search for natural safe alternatives. Vitamin D (VD) has been acknowledged as an essential factor in cardiovascular health. Thus, we aimed to illustrate the impact of different ...
Top fields of study
Diabetes mellitus