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Pathology & Oncology Research
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2.43
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2315
Papers 2347
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#1Haifeng ZhuH-Index: 1
#2Yongping YouH-Index: 1
Last.Lei ShiH-Index: 1
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#1Fatma A. Mohamed (Minia University)H-Index: 2
#2El Zahraa Ibrahim Khalil (Minia University)
Last.Nisreen D.M. Toni (Minia University)H-Index: 1
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#1Levente KuthiH-Index: 1
#2Áron SomoráczH-Index: 10
Last.Béla IványiH-Index: 22
view all 13 authors...
Xp11.2 translocation carcinoma is a distinct subtype of renal cell carcinoma characterized by translocations involving the TFE3 gene. Our study included the morphological, immunohistochemical and clinicopathological examination of 28 Xp11.2 RCCs. The immunophenotype has been assessed by using CA9, CK7, CD10, AMACR, MelanA, HMB45, Cathepsin K and TFE3 immunostainings. The diagnosis was confirmed by TFE3 break-apart FISH in 25 cases. The ages of 13 male and 15 female patients, without underlying r...
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#1Masaaki OikawaH-Index: 5
#2Toshikazu TanakaH-Index: 36
Last.Chikara Ohyama (Hirosaki University)H-Index: 31
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This study aimed to determine the prognostic factors associated with biochemical recurrence (BCR) after radical prostatectomy (RP) in patients with pathological T2 (pT2) prostate cancer (PCa) and negative resection margin (RM) status at a single institution. In this retrospective study, we examined 386 patients who were diagnosed with pT2 PCa with negative RM after RP. The length of the tumor was provided for each biopsy core and the overall percentage of PCa was calculated by a pathologist at o...
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#1Koroku Kato (Kanazawa University)H-Index: 14
#2Hiroki Miyazawa (Kanazawa University)H-Index: 1
Last.Shuichi Kawashiri (Kanazawa University)H-Index: 21
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We evaluated the clinical and prognostic value of the protein expression of caveolin-1 (CAV1) and p16 at the primary site and metastatic lymph nodes of oral squamous cell carcinoma (OSCC). Primary site specimens from 80 OSCC cases were randomly selected and lymph node specimens from 15 preserved metastatic lymph nodes from among those patients were selected for examination. We evaluated the CAV1 and p16 expression at both the primary site and metastatic lymph nodes, and analyzed the patients’ cl...
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#1Nahla E. El-Ashmawy (Tanta University)H-Index: 6
#2Eman G. Khedr (Tanta University)H-Index: 5
Last.Nada N. Helmy (Tanta University)
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Benign prostatic hyperplasia (BPH) is considered a normal part of the aging process in men, and is characterized by an imbalance between cell proliferation and apoptosis. Our study aimed to investigate the potential protective role of silymarin (SIL) against testosterone-induced BPH in rats and to elucidate the molecular mechanisms underlying SIL pro-apoptotic and anti-proliferative effects. Forty adult male Wistar rats were divided equally into four groups: control group, BPH group (3 mg/kg tes...
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#1Marcell Baranyi (Semmelweis University)H-Index: 1
#2Dominika Rittler (Semmelweis University)H-Index: 1
Last.Tamas GarayH-Index: 9
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Bisphosphonates, despite proven antitumor effect in vitro in many tumor types, are currently used only for treatment of osteoporosis and bone metastasis. Colorectal cancer is the third most commonly diagnosed type of cancer and lacks targeted therapy for RAS or RAF mutation carrying cases. A new lipophilic bisphosphonate showed promising results in lung cancer models, but their effect on colorectal cancer cells was not investigated excessively. Antitumor effects and impact on RAS-related signali...
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#1Ruolan Dong (HUST: Huazhong University of Science and Technology)
#2Jiawei Liu (HUST: Huazhong University of Science and Technology)H-Index: 1
Last.Wei Ping (HUST: Huazhong University of Science and Technology)
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Lung cancer (LC) continues to be the leading cause of cancer-related deaths worldwide and the prognosis remains poor worldwide. At present, the long non-coding RNAs (lncRNAs) was considered as a part of competing endogenous RNA (ceRNA) network act as natural microRNA (miRNA) sponges to regulate protein-coding gene expression. However, functional roles of lncRNA-mediated ceRNAs in LC are insufficiently understood. To classify the specific mechanism of lung adenocarcinoma (LUAD) and lung squamous ...
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#1Rosa Jahangiri (MUMS: Mashhad University of Medical Sciences)H-Index: 3
#2Fatemeh Mosaffa (MUMS: Mashhad University of Medical Sciences)H-Index: 15
Last.Khadijeh Jamialahmadi (MUMS: Mashhad University of Medical Sciences)H-Index: 8
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Tamoxifen is the most important treatment component in estrogen receptor positive (ER+) breast carcinoma patients. Tamoxifen resistance incidence presents an important obstacle in clinical treatment. Mechanisms underlying tamoxifen refractory are not completely understood. Although elevated expression of Gankyrin (P28GANK) and stem cell markers Nanog, Oct-4 and Sox-2 have been reported in breast carcinoma, their role in tamoxifen resistance progression has not been explored. In the present study...
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