Cell Stress & Chaperones
Papers 1542
1 page of 155 pages (1,542 results)
#1Ryoji Kojima (Meijo University)H-Index: 17
#2Kei-ichi Uchiya (Meijo University)H-Index: 15
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Human αB-crystallin (HSPB5) is frequently modified post-translationally by UV radiation, oxidation, and age-associated processes, which complicates functional analyses of the protein using natural sources. Thus, determining the biological function of HSPB5 at the molecular structure level requires unmodified protein. Here, we employed an Escherichia coli cell-free protein synthesis system to prepare unmodified, functionally active human HSPB5. An S30 extract prepared from E. coli strain BL21 (DE...
#1Bao-Xiang Zhang (WMU: Weifang Medical University)H-Index: 1
#2Jing Wang (WMU: Weifang Medical University)
Last.Cai-Xia Tu (Dalian Medical University)H-Index: 7
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Vitiligo is a chronic, autoimmune destruction of melanocytes, resulting in progressively expanding depigmented skin patches. Severity of the disorder, which affects approximately 1% of humans, may be mitigated using topical corticosteroids combined with phototherapy; along with other clinical strategies; however, no definitive cures are currently available. Here, the capacity of apigenin, a plant-derived aglycone, to inhibit oxidative stress–mediated melanocyte depletion in vitro using a PIG3V v...
#1Nektarios Barabutis (ULM: University of Louisiana at Monroe)H-Index: 3
Heat shock protein 90 is a highly conserved molecular chaperone, essential for cellular survival under diverse environments. Since this protein is employed by tumors to promote their prevalence, heat shock protein 90 inhibitors have been developed to oppose malignancies. The anti-cancer effects of those compounds appear to be associated with anti-inflammatory properties. Thus, ongoing laborious efforts investigate the possible application of those agents towards inflammatory disorders of the lun...
#1Qingkang LyuH-Index: 1
#2Irene S. LudwigH-Index: 12
Last.Femke BroereH-Index: 21
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#1Wenjuan Song (NAU: Nanjing Agricultural University)
#2Le Sheng (NAU: Nanjing Agricultural University)
Last.Yafei Cai (NAU: Nanjing Agricultural University)H-Index: 2
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Bovine mastitis is a common inflammatory disease caused by various factors. The main factor of mastitis is pathogenic microorganism infection, such as Staphylococcus aureus, Escherichia coli, and Streptococcus. Cronobacter sakazakii (C. sakazakii) is a newly discovered pathogenic bacteria in milk products, which seriously threat human health in recent years. At present, it has not been reported that the pathogenesis of mastitis is caused by C. sakazakii. This study investigated the inflammation ...
#1Sandra M. Casas (Louisiana State University Agricultural Center)H-Index: 6
#2Jerome F. La Peyre (Louisiana State University Agricultural Center)H-Index: 22
A major problem of storing and shipping eastern oysters (Crassostrea virginica) from the Northern Gulf of Mexico in summer and early fall is their elevated mortality. A study was therefore conducted to determine whether heat shocking the oysters or conditioning them to aerial exposure prior to harvest could reduce their mortality during cold storage. Increasing the levels of stress proteins in bivalves has been shown to reduce their mortality when exposed to additional stressors. In this study, ...
#1Rachel Kuta (Montreal Neurological Institute and Hospital)H-Index: 1
#2Nancy Larochelle (Montreal Neurological Institute and Hospital)H-Index: 11
Last.Heather D. Durham (Montreal Neurological Institute and Hospital)H-Index: 29
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Upregulation of heat shock proteins (HSPs) is an approach to treatment of neurodegenerative disorders with impaired proteostasis. Many neurons, including motor neurons affected in amyotrophic lateral sclerosis (ALS), are relatively resistant to stress-induced upregulation of HSPs. This study demonstrated that histone deacetylase (HDAC) inhibitors enable the heat shock response in cultured spinal motor neurons, in a stress-dependent manner, and can improve the efficacy of HSP-inducing drugs in mu...
Top fields of study
Molecular biology
Heat shock protein