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Stress
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#1Devrim Saribal (Istanbul University)H-Index: 2
#2Asli Kirectepe Aydin (ITU: Istanbul Technical University)H-Index: 3
Last. Mustafa Balkaya (BAU: Bahçeşehir University)H-Index: 1
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A growing number of studies in humans have linked chronic stress, particularly during early life, to telomere shortening and increased oxidative stress. The effect of stress on telomerase activity, however, is understudied. Given the importance of telomere attrition in a wide range of diseases and immunosenescence, further research to elucidate the mechanisms by which stress alters telomere dynamics is required. However, animal studies are lacking, and it is not clear whether widely used stress ...
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#1Giulia TreccaniH-Index: 10
#2Anna-Lena Schlegelmilch (University of Mainz)
Last. Malin Wennström (Lund University)H-Index: 17
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Objective: The suggested link between major depression disorder (MDD) and blood brain barrier (BBB) alterations supports an impact on the neurovascular unit in this disease condition. Here we investigate how pericytes, a major component in the neurovascular unit, respond to stress, stress hormones, proinflammatory cytokine and depression.Method: Hippocampal sections of chronic unpredictable stressed (CMS) rats, MDD patients and respective controls were immuno-stained against NG2, where the numbe...
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#1Martin VodičkaH-Index: 4
#2Anna VavřínováH-Index: 4
Last. Michal BehuliakH-Index: 16
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Fischer 344 (F344) rats are characterized by the hyper-reactive hypothalamic-pituitary-adrenal (HPA) axis to stressful stimuli, while Lewis (LEW) rats are considered to be hypo-reactive. We studied stress-induced cardiovascular, neuroendocrine and behavioral responses of adult male F344 and LEW rats subjected to the single (120 min) or the repeated restraint stress (daily 120 min for one week). Mean arterial pressure (MAP) and heart rate (HR) were measured in the restrained rats (n = 7-8 for eac...
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#1Simon Skau (University of Gothenburg)H-Index: 1
#2Ingibjörg H. Jonsdottir (University of Gothenburg)H-Index: 28
Last. H. Georg Kuhn (University of Gothenburg)H-Index: 34
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Patients with stress-related Exhaustion Disorder (ED) have problems with memory andexecutive function. These problems have been associated with deviant activity in prefrontal cortex (PFC). We inves...
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#1Dan Farbstein (TAU: Tel Aviv University)H-Index: 1
#2Nurit Hollander (TAU: Tel Aviv University)H-Index: 15
Last. Chaim G. Pick (TAU: Tel Aviv University)H-Index: 40
view all 11 authors...
The aim of this study was to investigate the behavioral, immunological, and neurological effects of long-term isolation in an animal model. Male C3H/eB mice wereraised in either social isolation or standard conditions for 6 weeks. At 10 weeks, each group was further divided into 3 sets. (A) Physical strength and behavior were evaluated with the grip strength, hot plate, staircase, and elevated plus-maze tests. Natural-killer cell activity and lymphocyte proliferation were measured. (B) Half the ...
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#1María Banqueri (Nencki Institute of Experimental Biology)H-Index: 2
#2Alba Gutiérrez-Menéndez (CSIC: Spanish National Research Council)H-Index: 1
Last. Jorge Luis Arias Pérez (CSIC: Spanish National Research Council)H-Index: 25
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Unfortunately, adverse environments in early life are frequently found in most human populations. Early life stress leads to diverse cognitive impairments, some of them related to learning and memory and executive functions such as working memory (WM). We employ an animal model of early stress using repeated maternal separation (MS) for four hours a day on 21 consecutive days, pre-weaning. In adulthood, we tested their spatial WM using the Morris water maze. MS subjects showed a marked delay in ...
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#1Daniela Jezova (SAV: Slovak Academy of Sciences)H-Index: 38
#2Jana Trebatická (Comenius University in Bratislava)H-Index: 10
Last. Natasa Hlavacova (SAV: Slovak Academy of Sciences)H-Index: 14
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Measurement of basal and stress-induced salivary alpha-amylase activity may help to understand autonomic nervous system disturbance in mental disorders. The potential sympathetic nervous system dys...
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#1Mohammad Mehdi Ommati (Shanxi Agricultural University)H-Index: 3
#2Ali Amjadinia (Shiraz University of Medical Sciences)
Last. Reza Heidari (Shiraz University of Medical Sciences)H-Index: 21
view all 6 authors...
Cholestasis is a multifaceted clinical complication. Obstructive jaundice induced by bile duct ligation (BDL) is known as an animal model to investigate cholestasis and its associated complications...
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#1Alexey Sarapultsev (RAS: Russian Academy of Sciences)H-Index: 3
#2Petr Sarapultsev (RAS: Russian Academy of Sciences)H-Index: 4
Last. Vadim Tseilikman (SUSU: South Ural State University)H-Index: 3
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There is evidence that plasma cortisol concentration can be either increased or decreased in patients with depression and related anxiety and stress-related disorders; the exact pathophysiological ...
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#1Katja Petrowski (TUD: Dresden University of Technology)H-Index: 19
#2Susann Wichmann (University of Mainz)H-Index: 5
Last. Clemens Kirschbaum (TUD: Dresden University of Technology)H-Index: 107
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AbstractThe role of cortisol as a premorbid vulnerability factor for trauma sequelae remains unclear. Furthermore, the onset of long-term endocrine changes in response to first time trauma as a fun...
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