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Diabetology & Metabolic Syndrome
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2.36
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1147
Papers 1174
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Background Chloride is a key electrolyte that regulates the body fluid distribution. Accordingly, manipulating chloride kinetics by selecting a suitable diuretic could be an attractive strategy for correcting body fluid dysregulation. Therefore, this study examined the effects and contributing factors of a sodium–glucose cotransporter-2 inhibitor (SGLT2i) on the serum chloride concentration in type 2 diabetic (T2DM) patients without heart failure (HF).
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#1Fathimah S. Sigit (UI: University of Indonesia)
#2Dicky L. Tahapary (UI: University of Indonesia)H-Index: 4
Last.Renée de Mutsert (LUMC: Leiden University Medical Center)H-Index: 27
view all 7 authors...
Background The prevalence of metabolic syndrome varies among populations with different ethnicities. Asian populations develop metabolic complications at lower amounts of adiposity than western populations. The role of abdominal obesity in the metabolic differences between the two populations is poorly understood.
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Background New technologies are changing diabetes treatment and contributing better outcomes in developed countries. To our knowledge, no previous studies have investigated the comparative effect of sensor-based monitoring on glycemic markers in developing countries like Brazil. The present study aims to evaluate the use of intermittent Continuous Glucose Measurements (iCGM) in a developing country, Brazil, regarding (i) frequency of glucose scans, (ii) its association with glycemic markers and ...
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#1Lanting Xiang (First Affiliated Hospital of Wenzhou Medical University)H-Index: 1
#2Qiongying Zhang (First Affiliated Hospital of Wenzhou Medical University)H-Index: 1
Last.Guorong Chen (First Affiliated Hospital of Wenzhou Medical University)H-Index: 1
view all 8 authors...
Diabetes mellitus is an important risk factor for cardiomyopathy. Increasing oxidative stress may be one of the main factors of diabetic cardiomyopathy. A13, a newly synthesized curcumin analog, was proved to be superior to curcumin in biological activity. However, little know about how A13 performed in diabetic models. In this study, we evaluated the ability of curcumin analog A13 to alleviate oxidative stress and ameliorate fibrosis in the myocardium, and explore the underlying mechanisms. Int...
1 CitationsSource
#1Jun Hung (Arizona College of Osteopathic Medicine)
#2Layla Al-Nakkash (MWU: Midwestern University)H-Index: 10
Last.Jeffrey H. Plochocki (UCF: University of Central Florida)H-Index: 9
view all 5 authors...
Background Leptin is an adipokine that regulates energy homeostasis and is also needed for normal bone growth and maintenance. Mutation in the lep gene, which characterizes the ob/ob mouse model, results in the development of obesity and type 2 diabetes mellitus, as well as reduced limb bone length and increased fracture risk. However, the relationship between limb bone length and growth plate cartilage structure in obese diabetic adolescents is incompletely understood. Here, we tested the hypot...
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#1Kan Sun (SYSU: Sun Yat-sen University)H-Index: 8
#2Diaozhu Lin (SYSU: Sun Yat-sen University)H-Index: 8
Last.Dan Liu (SYSU: Sun Yat-sen University)H-Index: 6
view all 10 authors...
Background Rational measures in estimating adiposity distribution in diabetic patients has yet to be validated. This study aims to provide insight about the possible links between routinely available body adiposity parameters and the development of both diabetes and insulin resistance.
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#1Jun-Koo YiH-Index: 1
#2Zae-Young Ryoo (KNU: Kyungpook National University)H-Index: 1
Last.Sunghyun Kim (KNU: Kyungpook National University)H-Index: 5
view all 6 authors...
Background Diabetes is characterized by hyperglycemia due to impaired insulin secretion and aberrant glucagon secretion resulting from changes in pancreatic islet cell function and/or mass. The aim of the present study was to investigate the effects of ginger on various tissues (i.e., pancreas, kidney, and liver) and insulin resistance in streptozotocin-induced diabetic mice. The pleasant aroma of ginger comes from the constituents present in its volatile oil, while its non-volatile pungent phyt...
1 CitationsSource
Insulin resistance is core cause of metabolic syndrome. Determining insulin resistance is one of the foremost requirements imperative to understanding the pathophysiology of disease. The gold standard “Euglycaemic clamp test” is cumbersome, long and non-feasible in routine clinical setups to diagnose metabolic syndrome. Various continuous and steady state insulin resistance indices are now available in literature. We plan to evaluate commonly utilized steady state insulin resistance indices dire...
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#1Omid Nikpayam (Tabriz University of Medical Sciences)H-Index: 1
#2Marziyeh Najafi (Shahid Beheshti University of Medical Sciences and Health Services)
Last.Neda Roshanravan (Tabriz University of Medical Sciences)H-Index: 5
view all 6 authors...
Many studies have investigated the relationship between coffee and diabetes. Evaluation of the current evidence on the effect of coffee intake on diabetes is critical. Therefore, we aimed to investigate the potential association between green coffee extract (GCE) and fasting blood glucose (FBG), insulin and homeostatic model assessment of insulin resistance (HOMA-IR) by pooling together the results from clinical trials. PubMed, Scopus and Google Scholar were searched for experimental studies whi...
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#1Jane S. S. P. Ferreira (USP: University of São Paulo)H-Index: 1
#2João P. Panighel (USP: University of São Paulo)
Last.Isabel C. N. Sacco (USP: University of São Paulo)H-Index: 25
view all 6 authors...
The stratification system from the International Working Group on the Diabetic Foot (IWGDF) was used to classify the participants as to the ulcer risk. However, it is not yet known what the classification groups’ individual deficits are regarding sensitivity, function, and musculoskeletal properties and mechanics. This makes it difficult to design proper ulcer prevention strategies for patients. Thus, this study aimed to investigate the foot function, foot strength and health of people with diab...
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Top fields of study
Endocrinology
Type 2 diabetes
Metabolic syndrome
Diabetes mellitus
Medicine