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Diabetology & Metabolic Syndrome
IF
2.36
Papers
1089
Papers 1143
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Background Insulin resistance is core cause of metabolic syndrome. Determining insulin resistance is one of the foremost requirements imperative to understanding the pathophysiology of disease. The gold standard “Euglycaemic clamp test” is cumbersome, long and non-feasible in routine clinical setups to diagnose metabolic syndrome. Various continuous and steady state insulin resistance indices are now available in literature. We plan to evaluate commonly utilized steady state insulin resistance i...
#1Junkoo YiH-Index: 1
#2Zae-Young Ryoo (KNU: Kyungpook National University)
Last.Sunghyun Kim (KNU: Kyungpook National University)H-Index: 4
view all 6 authors...
Background Diabetes is characterized by hyperglycemia due to impaired insulin secretion and aberrant glucagon secretion resulting from changes in pancreatic islet cell function and/or mass. The aim of the present study was to investigate the effects of ginger on various tissues (i.e., pancreas, kidney, and liver) and insulin resistance in streptozotocin-induced diabetic mice. The pleasant aroma of ginger comes from the constituents present in its volatile oil, while its non-volatile pungent phyt...
#1Jun Hung (MWU: Midwestern University)
#2Layla Al-Nakkash (MWU: Midwestern University)H-Index: 10
Last.Jeffrey H. Plochocki (UCF: University of Central Florida)H-Index: 9
view all 5 authors...
Background Leptin is an adipokine that regulates energy homeostasis and is also needed for normal bone growth and maintenance. Mutation in the lep gene, which characterizes the ob/ob mouse model, results in the development of obesity and type 2 diabetes mellitus, as well as reduced limb bone length and increased fracture risk. However, the relationship between limb bone length and growth plate cartilage structure in obese diabetic adolescents is incompletely understood. Here, we tested the hypot...
#1Kan Sun (SYSU: Sun Yat-sen University)H-Index: 6
#2Diaozhu Lin (SYSU: Sun Yat-sen University)H-Index: 7
Last.Dan Liu (SYSU: Sun Yat-sen University)H-Index: 6
view all 10 authors...
Background Rational measures in estimating adiposity distribution in diabetic patients has yet to be validated. This study aims to provide insight about the possible links between routinely available body adiposity parameters and the development of both diabetes and insulin resistance.
#1Homa Hodaei (Shahid Beheshti University of Medical Sciences and Health Services)
#2Mahsa Adibian (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 1
Last.Golbon Sohrab (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 6
view all 5 authors...
Background Diabetes mellitus is a common metabolic disorders in human and affect a lot of people around the world. Curcumin is a component of turmeric and in many studies therapeutic effects such as anti-hypertensive, anti-hyperlipidemia, anti-hyperglycemia for this substance are shown.
Background Familial partial lipodystrophy (FPL) is a rare genetic disease characterized by body fat abnormalities that lead to insulin resistance (IR). Clinical conditions linked to milder IR, such as type 2 diabetes (T2D) and metabolic syndrome, are associated with abnormalities of the hypothalamic–pituitary–adrenal (HPA) axis, but little is known about its activity in FPL.
#1Meng-jie Tang (Nantong University)
#2Jian‑bin Su (Nantong University)
Last.Xiao-hua Wang (Nantong University)H-Index: 5
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Fibroblast growth factor 19 (FGF19) takes part in maintaining the balance of glycolipids and may be involved in regulating the secretory activity of islet beta cells in patients with type 2 diabetes. This study aimed to evaluate the relationship between the levels of serum FGF19 and endogenous islet beta cell function in type 2 diabetic patients. Samples were obtained from 271 subjects: 85 drug-naive type 2 diabetes participants exclusively on lifestyle intervention (N-DM group), 122 type 2 diab...
#1Wei Zheng (Capital Medical University)H-Index: 2
#2Wenyu Huang (NU: Northwestern University)H-Index: 7
Last.Guanghui Li (Capital Medical University)H-Index: 2
view all 8 authors...
Background Polycystic ovary syndrome (PCOS) has been consistently associated with subsequent gestational diabetes mellitus (GDM). Women with PCOS showed a high prevalence of obesity, which raises the question regarding the role of obesity or PCOS pe ser in development of GDM. In this study we conducted a 2-phase study to compare the risk of GDM and its associated early pregnancy metabolic factors in women with and without PCOS, stratified by pre-pregnancy body mass index (BMI).
#1Afsaneh Bakhtiari (Babol University of Medical Sciences)H-Index: 3
#2Karimollah Hajian-Tilaki (Babol University of Medical Sciences)H-Index: 16
Last.Fatemeh Nasiri-Amiri (Babol University of Medical Sciences)H-Index: 3
view all 4 authors...
Background There are many studies on the health effects of soy, only a few describe the effects of the simultaneous use of two types of soy on multiple components of metabolic syndrome (MetS). The present study was designed to determine the effects of roasted soy-nut and textured soy protein (TSP) intake on clinical and metabolic status of older women with MetS borderline parameters.
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