Seizure-european Journal of Epilepsy
Papers 3837
1 page of 384 pages (3,837 results)
#1Lucy Deng (USYD: University of Sydney)
#2Alan Ma (USYD: University of Sydney)
Last. Simone L. Ardern-Holmes (USYD: University of Sydney)H-Index: 10
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Abstract Purpose SCN1A variants cause a spectrum of epilepsy syndromes from Dravet Syndrome, a severe epileptic encephalopathy of early infancy to the milder disorder of genetic epilepsy with febrile seizures plus (GEFS+). These genetic epilepsies are associated with increased risk of poor outcome including complications of status epilepticus and early mortality. Individualised management of young children known to be at increased risk should be considered, such as around vaccination management....
Abstract Purpose The cerebral glymphatic system, particularly the Virchow–Robin Spaces (VRS), plays an important role in waste clearance from the brain. Idiopathic generalized epilepsy (IGE) is a common epilepsy type associated with blood-brain-barrier dysfunction, abnormal exchange of cerebrospinal fluid and interstitial fluid. These disorders may be reflected in the glymphatic system. Therefore, this study investigated the relationships between visible VRS on MRI and seizures, to detect change...
Abstract Purpose To identify the predictors of seizure recurrence after a first seizure (FS) presentation to an emergency service. Methods The clinical characteristics of FS patients presenting to the emergency department (ED) of our university hospital from January 2001 to December 2014 were retrospectively reviewed. Recurrence of seizures following the FS was classified as: early recurrence (0–1 month), intermediate recurrence (>1–3 months), and late recurrence (>3–12 months). The significant ...
#2Christin EltzeH-Index: 2
Last. Friederike Moeller (GOSH: Great Ormond Street Hospital)H-Index: 2
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Abstract Purpose Failure to recognise involvement of the insula / opercula (I/O) region is associated with poor outcome in epilepsy surgery. Recognition is challenging due to high connectivity with adjacent structures resulting in variable and misleading semiology, often subjective and therefore likely to be underreported by children. In this study we explored prevalence and characteristics of I/O involvement in paediatric patients undergoing sEEG exploration. Method We retrospectively included ...
#1Hajo M. Hamer (FAU: University of Erlangen-Nuremberg)H-Index: 20
#2Martin Holtkamp (Charité)H-Index: 23
Last. Andreas Schulze-Bonhage (University Medical Center Freiburg)H-Index: 56
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Abstract Purpose Current trials on adjunctive treatment with antiseizure drugs often do not reveal results which are relevant for clinical practice. Method Therefore, an interdisciplinary group of German experts discussed a new framework for future antiseizure drug (ASD) trials in adults. This group included members of the executive board of the German Society of Epileptology, of the German institutes for health technology assessment (HTA), of patient organizations and of drug manufacturers. Agr...
#1Sahar A. Harby (Alexandria University)
#2Rasha A. Nassra (Alexandria University)H-Index: 5
Last. Cherine A. Ismail (Alexandria University)H-Index: 4
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Abstract Objective Therapeutic drug monitoring (TDM) is increasingly recommended in antiepileptic drug (AED) therapy, yet a complex relationship exists between the unbound-drug serum concentration (Cu.serum) as a monitoring biomarker and clinical efficacy. The study was designed to investigate the validity of the intracellular unbound-drug concentration in Peripheral Blood Mononuclear Cells (Cu.PBMC) as a feasible TDM tool in relation to levetiracetam (LEV). Methods Patients from epilepsy out-pa...
#1Sunil Pradhan (SGPGIMS: Sanjay Gandhi Post Graduate Institute of Medical Sciences)H-Index: 25
#2Animesh Das (SGPGIMS: Sanjay Gandhi Post Graduate Institute of Medical Sciences)H-Index: 1
Last. Ananya Das (SGPGIMS: Sanjay Gandhi Post Graduate Institute of Medical Sciences)
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Abstracts Purpose The duration of antiepileptic drug (AED) treatment in the management of seizures due to ring enhancing lesions (REL) remains a matter of debate. We undertook a prospective cohort study to look into the seizure patterns and incidence of recurrence in association with two of the most common causes of RELs after gradually stopping AEDs at least 18 months after acheiving seizure control. Methods Ninety patients with neurocysticercosis (NCC) and twenty-nine patients with tuberculoma...
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