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Cerebrovascular Diseases
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#1Adnan I Qureshi (MU: University of Missouri)H-Index: 36
#2Lydia D. Foster (MUSC: Medical University of South Carolina)H-Index: 13
Last. Jose I. Suarez (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 38
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OBJECTIVE To study the effect of intensive blood pressure reduction in patients with moderate to severe intracerebral hemorrhage (ICH) within the subjects recruited in Antihypertensive Treatment of Acute Cerebral Hemorrhage 2 trial. DESIGN Randomized, multicenter, 2 group, open-label clinical trial. SETTING A total of 110 sites in the USA, Japan, China, Taiwan, South Korea, and Germany. PATIENTS A total of 1,000 patients underwent randomization from May 2011 till September 2015. INTERVENTIONS We...
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#1Fergus W. Gardiner (ANU: Australian National University)H-Index: 4
#2Lara Bishop (ANU: Australian National University)H-Index: 3
Last. Klaus FassbenderH-Index: 34
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Introduction Rural, remote, and Indigenous stroke patients have worse stroke outcomes than urban Australians. This may be due to lack of timely access to expert facilities. Objectives We aimed to describe the characteristics of patients who underwent aeromedical retrieval for stroke, estimate transfer times, and investigate if flight paths corresponded with the locations of stroke units (SUs) throughout Australia. Methods Prospective review of routinely collected Royal Flying Doctor Service (RFD...
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Background and aims Syphilis and stroke are high prevalent diseases in south Brazil and estimates of concomitance and possible role of syphilis in acute stroke are lacking. Our aims are to estimate the prevalence of syphilis and neurosyphilis (NS) in a cohort of tertiary stroke center. Methods We reviewed all hospital records of stroke/transitory ischemic attack (TIA) using International Classification of Diseases, 10th revision, at discharge, frequency of syphilis screen, serology positivity, c...
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#1Benjamin Yong-Qiang Tan (University Health System)H-Index: 6
#2Jamie Sin Ying Ho (University of Cambridge)
Last. Bernard Canaud (University Health System)H-Index: 53
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INTRODUCTION It is unclear which surrogate of atrial cardiopathy best predicts the risk of developing a recurrent ischemic stroke in embolic stroke of undetermined source (ESUS). Left atrial diameter (LAD) and LAD index (LADi) are often used as markers of left atrial enlargement in current ESUS research, but left atrial volume index (LAVi) has been found to be a better predictor of cardiovascular outcomes in other patient populations. OBJECTIVE We aim to compare the performance of LAVi, LAD, and...
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BACKGROUND Stent retriever technology has evolved, and significantly longer devices have become available for mechanical thrombectomy (MT) of large cerebral vessel occlusions in ischemic stroke. We hypothesized that increased stent retriever length may improve the rate of complete angiographic reperfusion and decrease the respective number of attempts, resulting in a better clinical outcome. METHODS Retrospective analysis of patients with large vessel occlusion in the anterior and posterior circ...
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#1Fumihiro Sakakibara (Hyogo College of Medicine)
#2Shinichi Yoshimura (Hyogo College of Medicine)H-Index: 35
Last. Takeshi Morimoto (Hyogo College of Medicine)H-Index: 47
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BACKGROUND AND PURPOSE Diffusion-weighted imaging-fluid-attenuated inversion recovery (DWI-FLAIR) mismatch is an early sign of acute ischemic stroke. DWI-FLAIR mismatch was reported to be valuable to select patients with unknown onset stroke who are eligible to receive intravenous thrombolysis (IVT), but its utility is less studied in patients undergoing mechanical thrombectomy (MT) for acute large vessel occlusion (LVO). We thus investigated the functional outcomes at 90 days between patients w...
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BACKGROUND Severe leukoaraiosis (LA) is an established risk factor for poor outcome after mechanical thrombectomy (MT) for large vessel occlusion stroke. There is uncertainty whether this association also applies to successfully recanalized patients with M1 segment middle cerebral artery (MCA) occlusions. METHODS A retrospective single-centre study of patients with successful reperfusion (thrombolysis in cerebral infarction, TICI 2b or 3) after MT for an M1 MCA occlusion was performed over a 7-y...
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#1Yeon-Jung Kim (UOU: University of Ulsan)H-Index: 7
#2Bum Joon Kim (Kyung Hee University)H-Index: 13
Last. Dong-Wha Kang (UOU: University of Ulsan)H-Index: 45
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BACKGROUND Genetic variants may play a role in determining the location of cerebral atherosclerosis. We aimed to investigate the association between RNF213, MMP2, and genetic polymorphisms linked to vascular tortuosity with the location of cerebral arterial atherosclerosis. METHODS A prospective case-control study was conducted on patients with ischemic stroke and age- and sex-matched stroke-free controls. The stroke patients were categorized into those with intracranial artery atherosclerosis (...
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#1Michael Moussouttas (RU: Rutgers University)H-Index: 1
#2Nikolaos I.H. Papamitsakis (SUNY Downstate Medical Center)H-Index: 1
BACKGROUND: Two recent cerebrovascular studies, Clopidogrel (Clo) in High-risk patients with Acute Nondisabling Cerebrovascular Events (CHANCE) and Platelet-Oriented Inhibition in New TIA and minor ischemic stroke (POINT), have purportedly demonstrated the superiority of early dual antiplatelet therapy (DAPT), using aspirin (ASA) plus Clo, in comparison to ASA alone following the occurrence of acute minor cerebral infarction or transient ischemic attack. However, limitations to these trials exis...
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