Metabolic Brain Disease
Papers 2101
1 page of 211 pages (2,101 results)
#1Ashraf Y. Al-Brakati (Taif University)H-Index: 2
#2Alaa Jameel A. Albarakati (UQU: Umm al-Qura University)H-Index: 1
Last. Ahmed M. A. Akabawy (Helwan University)H-Index: 1
view all 13 authors...
Diabetes mellitus is an increasing metabolic disease worldwide associated with central nervous system disorders. Coffee is a widely consumed beverage that enriched with antioxidants with numerous medicinal applications. Accordingly, the present study aimed to investigate the therapeutic potential of orally administered green coffee bean water extract (GCBWE) against cortical damage induced by high fat diet (HFD) followed by a single injection of streptozotocin (STZ) in rats. Metformin (Met) was ...
#1Saida Haider (KU: University of Karachi)H-Index: 18
#2Syeda Madiha (KU: University of Karachi)H-Index: 5
Last. Zehra Batool (KU: University of Karachi)H-Index: 10
view all 3 authors...
Pistachio contains polyphenolic compounds including flavonoids and anthocyanins which have antioxidant and antiinflammatory activity. Present study was aimed to evaluate the protective effects of pistachio on neurobehavioral and neurochemical changes in rats with Parkinson’s disease (PD). Animal model of PD was induced by the injection of rotenone (1.5 mg/kg/day, s.c.) for 8 days. Pistachio (800 mg/kg/day, p.o.) was given for two weeks in both pre- and post-treatment. At the end of treatment bra...
#1Jalal GharesouranH-Index: 8
#2Abbas Jalaiei (Tabriz University of Medical Sciences)
Last. Mohammad Taheri (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 12
view all 11 authors...
Pompe disease (PD) is a rare autosomal recessive multi-systemic lysosomal storage disorder, caused by mutations in the acid alpha-glucosidase (GAA) gene located on 17q25.2-q25.3. It is one of about 50 rare genetic diseases categorized as lysosomal storage disorders. This disease is characterized by a range of different symptoms related to acid alpha-glucosidase deficiency. Mutation recognition in the GAA gene can be very significant for purposes such as therapeutic interference, early diagnosis ...
#1Weijia Han (Capital Medical University)
Last. Zhongping Duan (Capital Medical University)
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Minimal hepatic encephalopathy (MHE), which shows mild cognitive impairment, is a subtle complication of cirrhosis that has been shown to affect daily functioning and quality of life. However, until 2014, relevant guidelines do not give much attention to the diagnosis and treatment of MHE, resulting in patients being ignored and denied the benefits of treatment. In this review, we summarize recent cognition-based research about (1) alteration of nerve cells, including astrocytes, microglial cell...
#1Mir Salar Kahaei (Shahid Beheshti University of Medical Sciences and Health Services)
#2Soudeh Ghafouri-Fard (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 19
Last. Mohammad Taheri (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 12
view all 6 authors...
The Brain cytoplasmic 200 RNA (BC200 RNA) is neuron-specific lncRNA with putative roles in normal aging and in the pathogenesis of Alzheimer's disease. Its role in the neuron plasticity has also been documented. In the current study, we genotyped a single nucleotide polymorphism (SNP) within this lncRNA (rs4404327) in a population of Iranian patients with diverse neuropsychiatric conditions including substance addiction (n = 315), attention deficit hyperactive disorder (ADHD) (n = 53), bipolar 1...
#1Mohammad Hossein Sakhaee (MUMS: Mashhad University of Medical Sciences)
#2Seyed Amir Hossein Sayyadi (MUMS: Mashhad University of Medical Sciences)
Last. Fatemeh Forouzanfar (MUMS: Mashhad University of Medical Sciences)H-Index: 7
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Injured somatosensory nervous system cause neuropathic pain which is quite difficult to treat using current approaches. It is therefore important to find new therapeutic options. We have analyzed cedrol effect on chronic constriction injury (CCI) induced neuropathic pain in rats. The mechanical and thermal hypersensitivity were evaluated using the von Frey filament, radiant heat and acetone drop methods. The changes in the levels of biomarkers of oxidative stress including malondialdehyde (MDA) ...
#1Lei Zhao (SEU: Southeast University)H-Index: 4
#2Longfei Du (SEU: Southeast University)H-Index: 2
Last. Yuan Zhang (SEU: Southeast University)H-Index: 10
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In the original publication of this article, wrong western blot images were inadvertently included in Fig. 2 and Fig. 3. The corrected figures are shown below. The authors declare that these amendments do not change the results or conclusions of their paper, and apologize for this oversight.
#1Babak Rasouli (Aja University of Medical Sciences)
#2Laya Ghahari (Aja University of Medical Sciences)H-Index: 2
Last. Saeideh Naeimi (Semnan University)H-Index: 2
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Brain stroke is one of the causes of human death and disability worldwide. Global ischemia results in the accumulation of free radicals in the neurons. It leads to histologically brain damage. The CA1 region of the hippocampus is a sensitive area for free radicals. This study investigated the combined therapy of the Granulocyte colony stimulating factor (G-CSF) and the Intravenous lipid emulsion (ILE). These neuroprotective agents play a role in the regeneration of neurons. They improve the lear...
#1Zeinab Shirvani Farsani (Shahid Beheshti University)H-Index: 3
#2Alireza Zahirodin (Shahid Beheshti University of Medical Sciences and Health Services)
Last. Bahar Naghavi Gargari (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 3
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Bipolar disorders are known as chronic, recurrent, and heterogenic diseases. Regarding, diagnosis and treatment of them are very complex. The molecular mechanism and pathophysiology of bipolar disorder are slightly known. Accordingly, long noncoding RNAs are considered as one of the main factors that are dysfunctional in many diseases such as the nervous system diseases. Hence, we aim to investigate the expression of two long non coding RNAs, MALAT1 and UCA1, in patients in bipolar disorder. The...
#1Juárez-Cedillo Teresa (Mexican Social Security Institute)
#2Calzada Fernado (Mexican Social Security Institute)
Last. Robles-Ramirez Roberto (Mexican Social Security Institute)
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: Because of the importance of cholesterol metabolism in the physiopathogenesis of dementia, and knowing the function of ATP-binding cassette A1 transporter (ABCA1) as a cholesterol flow pump at the cellular and cerebral level, it has been noted that the ABCA1 gene may be a good candidate for disease study. In order to evaluate the relationship between ABCA1 genetic variants and the risk of Alzheimer's disease and other dementia in Mexican individuals, we examined three ABCA1 polymorphisms locat...
Top fields of study
Hepatic encephalopathy
Diabetes mellitus