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Methods of biochemical analysis
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#1Enrique Carredano (GE Healthcare)H-Index: 2
#2Herbert Baumann (GE Healthcare)H-Index: 2
: The above discussion provides examples of how to utilize the possibilities arising from different scenarios, related to the level of information available, to identify low molecular weight organic molecule affinity ligands to target proteins. In Table 10.1 the different published results are summarized in terms of the structure of the ligand, the target protein, and a reference to the relevant publication. Common to all reported cases of small molecule affinity ligands is a considerably lower ...
5 CitationsSource
#1Bo ErssonH-Index: 12
#2Lars Rydén (Uppsala University)H-Index: 17
Last. Jan-Christer Janson (Uppsala University)H-Index: 25
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27 CitationsSource
#1Evert Karlsson (Uppsala University)H-Index: 11
#2Irwin Hirsh (GE Healthcare)H-Index: 1
13 CitationsSource
4 CitationsSource
#1Rainer WestermeierH-Index: 12
#2Angelika Görg (TUM: Technische Universität München)H-Index: 45
18 CitationsSource
4 CitationsSource
#1Pier Giorgio Righetti (Polytechnic University of Milan)H-Index: 73
#2Elisa Fasoli (Polytechnic University of Milan)H-Index: 21
Last. Sabina C. Righetti (Polytechnic University of Milan)H-Index: 17
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9 CitationsSource
#1Conan J. Fee (Cant.: University of Canterbury)H-Index: 19
#2James Van Alstine (GE Healthcare)H-Index: 5
: Separation of PEGylated proteins is challenging because PEG itself is a relatively inert, neutral, hydrophilic polymer and the starting point for PEGylation is a pure protein. Thus, other than molecular weight and size, differences in the physicochemical properties typically used to fractionate proteins may be slight between different PEGylated forms of a protein. The usual properties of electrostatic charge and molecular weight (size) form the basis of the most commonly used separation techni...
20 CitationsSource
1 CitationsSource
#1Zhiguo Su (CAS: Chinese Academy of Sciences)H-Index: 1
#2Diannan Lu (THU: Tsinghua University)H-Index: 24
Last. Zheng Liu (THU: Tsinghua University)H-Index: 32
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7 CitationsSource
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