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Journal of Global Pharma Technology
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The aim of the present study is to estimate the impact of intervention provided on screening programme to the participants and physicians and also proposed to study the factors influencing the physicians during prescribing antihypertensive and/ or antilipidemic agents. The study design was a cohort intervention study done at community pharmacies at Tamil Nadu, India. This was carried out for two years and data were collected from the patient record and interview. A screening prgoramme was arrang...
The purpose of present study was to investigate the antioxidant and anticancer activities of selected extracts of Kohautia aspera (Heyne ex Roth) Bremek. The chloroform, water and ethanolic extracts which are rich in phytoconstituents were subjected to DPPH photometric assay and standard MTT assay. The percentage of growth inhibition in antioxidant study increased with increasing concentration of extracts. The ethanolic extract showed better antioxidant activity followed by other extracts. The a...
The aim of the present study is to formulate a microsponge based release system contains ketoconazole for controlled release of drugs for an effective fungal treatment. Compatibility study involving drug and polymer mixture done by FTIR and was initiate to be compatible. Ketoconazole loaded microsponges were prepared by liquid-liquid suspension polymerization method using ethyl cellulose and hydroxypropyl methylcellulose as polymers with different drug polymer ratios. Later, formulated microspon...
N-acetyl-para-aminophenol (APAP) or paracetamol–copper based complex with [Cu(APAP) 2 (OH) 2 .H 2 O] formula and noted Cu-APAP has been synthesized and characterized on the basis of elemental analysis, conductivity, IR and thermal (TG/DTG), NMR and electronic spectral studies. The value of molar conductance of the complex indicates a non-electrolyte nature. The antimicrobial activity of the complex was evaluated against several pathogenic microorganisms to assess its potential. The copper comple...
ABSTRACT: Nanotechnology is a promising technique to increase the bioavailability of herbal medicines. The present study was formulated to evaluate nanoparticles using an ethanolic extract of Cocculus pendulus . The sonoprecipitation technique was employed for the preparation of nanosuspensions with poloxamer-407 and PVA with many trails and finally the optimized nanosuspension demonstrated a mean particle size, polydispersity index, and zeta potential of 536 nm, 0.256, and − 17.6 mV, respective...
Our mother nature is an abundant treasure of medicinal plants. Many of the plants have active constituents like alkaloids, benzoquinones, catechols, carotenoids, flavonoids, glycosides, flavanol glycosides, steroid glycosides, glycoalkaloids, terpenoids, monoterpenoids, diterpenoids, triterpene saponins, sterols and polyphenols which are proved to be having tissue rejuvenation property. Which can be made use in critical conditions like nephropathy which can be curable only with kidney transplant...
The objective of the present work was to formulate and to characterize multi unit floating drug delivery system of Dipyridamole to increase the bioavailability and sustain the drug release properties up to 8 h with more predictable drug release kinetics that avoids all or nothing emptying effect. Dipyridamole floating mini-tablets were prepared by effervescent approach with melt granulation and direct compression techniques alone and in combination using Hydroxypropyl methylcellulose (HPMC) K100...
#1Anton Smith A (Annamalai University)
Last. Arun R
view all 3 authors...
Objective : Development of analytical methods is in need for the estimation of drugs in pure and different pharmaceutical formulations. A simple, sensitive, rapid, accurate, precise and economic Spectrophotometric and Spectrofluorimetric method were developed and validated for Nadolol in pure and Pharmaceutical formulations. Methods : The wave length (λ max ) used for the estimation of Nadolol is 267nm by Spectrophotometry, excitation (λ Ex )-267nm and emission (λ Em )-300nm by Spectrofluorimetr...
The present study aimed to synthesize mangiferin AgNPs and evaluate its in vitro antioxidant and cytotoxic properties. Mangiferin AgNPs was prepared using silver nitrate solution and characterized by SEM and Zeta potential measurement. In-vitro antioxidant and cytotoxic studies of mangiferin and its AgNPs were conducted by using DPPH and MTT assay method, respectively. The synthesized mangiferin AgNPs with particle size ranges from 25.30 - 40.79 nm. The charge of mangiferin AgNPs were confirmed ...
Objective: Proteins and enzymes are marginally stable macromolecules along with certain additives for converting them into suitable drug formulation. The research in pharmaceuticals claims the suitability of wide and variety range of micelles, reverse micelles, unsaturated fatty acids and their esters with glycols act as a protective fence for such therapeutic macromolecules against denaturants in colloidal form. The present study, address preformulation and compatibility study of different addi...
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