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Published on 2019in F1000Research
Arkadiusz Dors3
Estimated H-index: 3
,
Ewelina Czyżewska-Dors3
Estimated H-index: 3
,
Grzegorz Woźniakowski
Background : The major pathogenic intestinal spirochetes affecting pigs during the growing- finishing stage of production include Brachyspira hyodysenteriae and Brachyspira pilosicoli . Infections by these pathogens, which affect the economics of pig production, can result in mortality, growth rate losses and substantial antibiotic costs. The aim of this study was to assess the current occurrence of B. hyodysenteriae and B. pilosicoli in Polish pig herds. Moreover, associations between the prese...
Published on 2019in F1000Research
Michael Walekhwa , Margaret Muturi1
Estimated H-index: 1
(KU: Kenyatta University)
+ 1 AuthorsBeatrice Muthoni Kabera1
Estimated H-index: 1
(Boston Children's Hospital)
Background: The spread of antimicrobial resistance threatens effective control and treatment of pneumococcal disease worldwide. In Kenya, an estimated one in every five children dies from pneumococcal disease every year. Of these, ≥50% are attributable to antibiotic resistance. Consequently, the WHO has recommended that continuous regional surveillance be done to detect early resistance to available antibiotics and make necessary changes. We therefore investigated antimicrobial susceptibility pa...
Published on 2019in F1000Research
Michelle B. Chen9
Estimated H-index: 9
(U of T: University of Toronto),
Antoninus Soosaipillai35
Estimated H-index: 35
(MSH: Mount Sinai Hospital, Toronto)
+ 1 AuthorsEleftherios P. Diamandis97
Estimated H-index: 97
Background: Traumatic brain injury (TBI) is a major cause of death and disability. Despite increased awareness, reliable biomarkers are urgently needed to aid in all forms of traumatic brain injury diagnosis and prognosis. Methods: Here, we aim to assess the diagnostic utility of known and novel TBI biomarkers in a pilot patient cohort of severe TBI (sTBI) patients and healthy controls. We analyzed concentrations of S100 calcium binding protein B (S100B), neuron specific enolase (NSE), human kal...
Published on 2019in F1000Research
Aziemah Azizi (UBD: Universiti Brunei Darussalam), Asrin Tengah3
Estimated H-index: 3
(UBD: Universiti Brunei Darussalam),
Mark I.R. Petalcorin (UBD: Universiti Brunei Darussalam)
Background: Phosphodiesterase-5 inhibitors (PDE5i) are the first line of drugs used for the treatment of erectile dysfunction. PDE5i inhibits the activities of phosphodiesterase-5 (PDE5) found in corpus cavernosum reducing production of guanosine monophosphate (GMP) that results in vasodilation of blood vessels thereby prolonging penile erection. Various counterfeit drugs adulterated with unknown levels of PDE5i pose a danger with reported undesirable adverse effects on patients. Methods: We dev...
Published on 2019in F1000Research
Mohamed Omaia (Cairo University), Maged M. Negm6
Estimated H-index: 6
(Cairo University)
+ 2 AuthorsAmal Othman
Background: Flare-ups may occur after root canal treatment which consist of acute exacerbation of asymptomatic pulpal and/or periradicular pathologic condition. The causative factors of interappointment pain include mechanical, chemical or microbial irritation to the pulp or periradicular tissues. The potential role of microorganisms in interappointment pain is why the success of endodontic treatment depends on complete eradication of microorganisms capable of causing an intraradicular or extrar...
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