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Cancer Medicine
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Papers 2993
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#1Madhumathy G. Nair (St. John's University)H-Index: 5
#2Jyothi S. Prabhu (St. John's University)H-Index: 6
Last. Sridhar T S (St. John's University)
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Despite the established benefits of long-term endocrine therapy, women with hormone receptor-positive breast cancer remain at risk for late relapse. The basis of this is multi-factorial including genetic, epigenetic, and host factors. In this study we have explored the epigenetic regulation of estrogen receptor (ER)-dependent molecular and cellular phenotype by hsa-miR-18a-5p using well-established human ER-positive (ER+) breast cancer cell lines. miR-18a was overexpressed in MCF7 and ZR-75-1 an...
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Last. Guangming LuH-Index: 1
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PURPOSE Laparoscopic nephrectomy (LN) has become the preferred method for renal cell carcinoma (RCC). Adequate preoperative assessment or intraoperative navigation is key to the successful implementation of LN. The aim of this study was to evaluate the clinical application value of mixed-reality-assisted surgical navigation (MRASN) in LN. PATIENTS AND METHODS A total of 100 patients with stage T1N0M0 renal tumors who underwent laparoscopic partial nephrectomy (LPN) or laparoscopic radical nephre...
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#1Zhiying Gao (Nanjing Medical University)
#2Jing Ni (Nanjing Medical University)H-Index: 3
Last. Guangfu Jin (Nanjing Medical University)H-Index: 34
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Most patients with gastric cancer (GC) are first diagnosed at stage III-IV and surgery resection remains the primary therapeutic modality for these patients. However, clinical staging used for prediction of those patients provides limited information. We collected clinicopathological data and disease-progression information from 508 patients with stage III-IV GC at three Chinese hospitals and 1298 patients from the Surveillance, Epidemiology, and End Results database. Based on the stepwise multi...
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OBJECTIVE Epidemiological evidence investigating serum uric acid and kidney cancer risk remains unclear. We conducted this study to examine the relationship between serum uric acid and the incidence and mortality of kidney cancer. METHODS This is a prospective analysis of 444 462 participants without any cancer from the UK Biobank. Serum uric acid was measured at baseline and the incidence and mortality of kidney cancer was determined through contact with the cancer and death registry. Cox regre...
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#1Jenerius A. Aminawung (Yale University)H-Index: 8
#2Jessica R. Hoag (Yale University)H-Index: 5
Last. Cary P. Gross (Yale University)H-Index: 52
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BACKGROUND Given the growth in dense breast notification (DBN) legislation in the United States, we examined the association between different types of DBN laws and supplemental screening behaviors among women. METHODS We surveyed in March-April 2018 a nationally representative sample of women aged 40-59 years who received a routine screening mammogram in the past 18 months. Survey items included the following topics regarding supplemental screening: discussing risks or benefits with a provider,...
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#1Francesco Latini (Uppsala University)H-Index: 4
#2Markus Fahlström (Uppsala University)H-Index: 5
Last. Mats Ryttlefors (Uppsala University)H-Index: 3
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BACKGROUND Low-grade gliomas (LGGs) are primary diffuse slow-growing brain tumors derived from glial cells. The management of these tumors is dependent on their location, which often harbors eloquent areas. We retrospectively recorded the location of diffuse gliomas to identify whether specific differences exist between the histological types. METHODS We analyzed 102 patients with previous histological diagnosis of WHO-II astrocytomas (62) and WHO-II oligodendrogliomas (40) according to WHO-2016...
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#1D. A. Barth (Medical University of Graz)
#2Carina Brenner (Medical University of Graz)
Last. Michael Stotz (Medical University of Graz)H-Index: 18
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BACKGROUND The advanced lung cancer inflammation index (ALI) was first introduced for prognosis prediction in lung cancer patients and since then evaluated in several other malignancies. However, in pancreatic cancer (PC) the ALI and its prognostic utility were only investigated in a comparably small and specific cohort of locally advanced PC patients treated with chemoradiotherapy. METHODS In our single-center cohort study, we included 429 patients with histologically verified PC who were treat...
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#2Yanpeng Chu (PKU: Peking University)
Last. Xiuqin Zhang (PKU: Peking University)
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BACKGROUND This study aimed to explore the possibility of serum tumor markers (TMs) combinations in assessing tumor metastasis in patients with lung cancer. METHODS We performed a retrospective analysis of 541 patients diagnosed with lung cancer between January 2016 and December 2017 at the Pneumology Department of Dazhou Central Hospital. Serum carcinoembryonic antigen (CEA), carbohydrate antigen (CA)125, CA153, CA199, CA724, cytokeratin 19 fragment (CYFRA), and neuron-specific enolase (NSE) le...
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#1H.J. Cho (Ajou University)H-Index: 9
#2Geum Ok Baek (Ajou University)H-Index: 1
Last. Suk Woo Nam (Catholic University of Korea)H-Index: 38
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Currently, a reliable serum biomarker for hepatocellular carcinoma (HCC) has not been established, particularly for early-stage HCC (single tumor 0.8. In our validation study, serum exo-miR-4661-5p could diagnose HCC in all stages (AUROC = 0.917), even in early stage (AUROC = 0.923), with a greater accuracy than other candidate serum exo-miRs and serum AFP. The panel composed of exo-miR-4661-5p and exo-miR-4746-5p was identified as the most accurate biomarker for early-stage HCC (AUROC = 0.947, ...
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#1Miyabi Miura (Kanazawa University)
#2Eishiro Mizukoshi (Kanazawa University)H-Index: 31
Last. Taro Yamashita (Kanazawa University)H-Index: 26
view all 14 authors...
BACKGROUND Immunotherapy for cancer patients has been the subject of attention in recent years. In this study, we investigated whether αβT-cell therapy causes changes in the host's immune cell profile, and if so, the effect of these changes on prognosis. METHODS Peripheral blood mononuclear cells (PBMCs) from 30 gastric cancer patients who had completed one course of αβT-cell therapy were analyzed. The peripheral blood immune cell profile was established using PBMCs by counting the frequency of ...
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