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Nihon rinsho. Japanese journal of clinical medicine
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Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are generally considered rare tumor. According to the recent studies, the number of patients had been increasing and frequently diagnosed as advanced stages. Surgery is the only possible way to cure GEP-NENs. However, the indication of surgical treatment for the patients with advanced GEP-NENs is limited, and for those patients other therapies such as radiofrequency ablation, transarterial chemoembolization, and/or systemic medical treat...
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Definition : Acute necrotizing encephalopathy (ANE) is a rare and fulminant complication of viral febrile infection, characterized by symmetric brain lesions affecting the bilateral thalamus.
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As bladder cancer is an age-related disease and an increase in patients with MIBC seems inevitable because of the aging population in Japan, muscle-invasive bladder cancer (MIBC) care in the elderly is likely to become a very common problem in daily practice. The gold standard for patients with MIBC is radical cystectomy (RC). However, elderly patients present with several comorbidities, and the geriatric patients with MIBC were not given po- tentially curative treatments, including RC. The opti...
The majority of fragile elderly individuals, such as the elderly in institutions for the elderly and those in home care use diaper or indwelling urethral catheters without careful considera- tion. Lower urinary tract dysfunction is hardly life threatening, but it impairs the dignity and quality of life of individuals. Inappropriate urinary management of elderly individuals leads to adverse changes in immobilization and dementia, and would ultimately render the disease untreatable. In order to bu...
Japan is an aging society. In general, an elderly population has urological diseases. Therefore, to understand the epidemiology of urological diseases is clinically very important. In a 15-year-longitudinal community-based study of Japanese men, prostate volume in- creased and lower urinary tract symptoms deteriorated. Many elderly Japanese females have pollakisuria. The 2015 cancer statistics suggest that the most common cancer in Japanese males is prostate cancer. Urothelial carcinoma develops...
Change by aging, which varies among individuals, influences physical and mental condi- tion, and social activity. Especially, illness accelerates the decreases of them in old adults. Surgical treatment for elderly patients might put a burden on their conditions and decrease activity of daily living if patients had adverse event and prolonged hospitalization. Because inadequate treatment is also associated with decreasing quality of life, it is necessary to pro- vide the adequate and effective tr...
Elderly people are at a high risk of experiencing problems with drug therapy due to age- related changes in the body, as well as exposure to many medications owing to multiple health problems. Medication-related adverse events are common amongst the elderly. Pharmacotherapy for benign prostatic hyperplasia or overactive bladder can generally im- prove lower urinary tract symptoms, whilst also improving the quality of life. However,;these drugs also have the potential to cause dangerous adverse e...
One of the major global demographic trends is the rapid ageing population, and the num- ber of people with ageing-related diseases has been increasing. In the urological field, ageing-related lower urinary tract symptoms (LUTS), especially detrusor hyperactivity with impaired contractility (DHIC), are commonly observed among elderly patients. However, such ageing-related LUTS and their backgrounds widely vary by individual. Previous reports using functional- and biological-investigations in rode...
The number of geriatric bladder cancer patients is now increasing in spite of little is known regarding the safety and efficacy of standard treatment for the patients due to luck of data in geriatric patients. Although they should be treated by modified standard treatment adjusted for their deteriorated physical activity, such treatment regimens are not established. Bladder preservation therapy could be recommended for geriatric patients with invasive bladder can- cer, which shows comparable sur...
Perioperative delirium and depression are characteristic of in elderly patients undergoing urological operation. The treatment for urological disease is stagnant, exchanged or inter- rupted by these complications. Furthermore, these complications may course to other more complications. Age, preoperative cognitive status, activities of daily living function, renal function and other factors were known for the risk factor of perioperative delirium. However, these complications should be managed im...
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