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Mastocytosis is a disorder characterized by clonal mast cell proliferation and accumulation within various organs, most commonly, the skin. Adult-onset mastocytosis is highly suggestive of a systemic involvement and the cases limited to the skin are uncommon. The authors report a 61-year-old male with pruritus associated with hyperpigmented maculopapular skin lesions and a positive Darier’s sign. The skin biopsy revealed spindle mast cells infiltrations. The bone marrow study was normal. He star...
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El manejo de la obstruccion maligna del tracto digestivo alto continua siendo un gran reto en la actualidad. En el momento del diagnostico la mayoria de los pacientes presentan un deterioro clinico avanzado debido al tumor y no son buenos candidatos para procedimientos quirurgicos mayores. En los ultimos anos las protesis metalicas autoexpandibles han emergido como una alternativa eficaz, segura y menos invasiva para el tratamiento de la obstruccion maligna esofagica y gastroduodenal. Se describ...
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Nocardiosis is a rare opportunistic infection caused by the bacteria Nocardia spp. It may present as a localized cutaneous infection or as an invasive infection (pulmonary, central nervous system or disseminated). The authors describe a 65-years-old woman, without a known cause of immunosuppression, admitted with fever, respiratory and constitutional symptoms. After an exhaustive etiological study, it was diagnosed a disseminated nocardiosis (pulmonary and central nervous system), in a probable ...
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Synchronous tumours are complex cases, being challenging to distinguish between primary neoplasms and metastatic disease, as well as to accurately determine the origin of metastasis. Although synchronous tumours are relatively rare, its incidence has increased over the years. The authors report on a patient with localized clear cell renal carcinoma and synchronous adenocarcinoma of the lung with solitary brain metastasis, highlighting the uncertainties of the therapeutic approach and the implica...
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