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Oxidative Medicine and Cellular Longevity
IF
4.87
Papers
3348
Papers 3571
1 page of 358 pages (3,571 results)
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Published on Sep 22, 2019in Oxidative Medicine and Cellular Longevity4.87
Stefania Schiavone15
Estimated H-index: 15
(University of Foggia),
Margherita Neri23
Estimated H-index: 23
(University of Ferrara),
Brian H. Harvey33
Estimated H-index: 33
(NWU: North-West University)
Published on Sep 19, 2019in Oxidative Medicine and Cellular Longevity4.87
Sander Bekeschus20
Estimated H-index: 20
(Leibniz Association),
Clarissa S. Schütz (University of Greifswald)+ 6 AuthorsMatthias B. Stope2
Estimated H-index: 2
(University of Greifswald)
Phosphorylated histone 2AX (γH2AX) is a long-standing marker for DNA double-strand breaks (DSBs) from ionizing radiation in the field of radiobiology. This led to the perception of γH2AX being a general marker of direct DNA damage with the treatment of other agents such as low-dose exogenous ROS that unlikely act on cellular DNA directly. Cold physical plasma confers biomedical effects majorly via release of reactive oxygen and nitrogen species (ROS). In vitro, increase of γH2AX has often been o...
Published on Sep 19, 2019in Oxidative Medicine and Cellular Longevity4.87
Cestmir Cejka13
Estimated H-index: 13
,
Jan Kossl2
Estimated H-index: 2
(Charles University in Prague)
+ 4 AuthorsJitka Čejková18
Estimated H-index: 18
Our previous research revealed that trehalose, a nonreducing disaccharide of glucose and an important stress responsive factor, proved to have anti-inflammatory, antiapoptotic, and particularly antioxidant properties in UVB-irradiated corneas. Trehalose reduced oxidative stress in corneas induced by UVB irradiation, by means of a decrease in the antioxidant/prooxidant imbalance in the corneal epithelium. In this study, we demonstrate that trehalose of 3% or 6% concentration in eye drops directly...
Published on Sep 18, 2019in Oxidative Medicine and Cellular Longevity4.87
Daofang Jiang1
Estimated H-index: 1
(Fudan University),
Chensheng Fu5
Estimated H-index: 5
(Fudan University)
+ 4 AuthorsXiaoli Zhang5
Estimated H-index: 5
(Fudan University)
Mitochondrial dysfunction has been implicated in the early stages or progression of many renal diseases. Improving mitochondrial function and homeostasis has the potential to protect renal function. Serum- and glucocorticoid-induced kinase 1 (SGK1) is known to regulate various cellular processes, including cell survival. In this study, we intend to demonstrate the effect and molecular mechanisms of SGK1 in renal tubular cells upon oxidative stress injury and to determine whether regulation of mi...
Published on Sep 18, 2019in Oxidative Medicine and Cellular Longevity4.87
Xiaoli Huang8
Estimated H-index: 8
(Sichuan Agricultural University),
Yang Feng1
Estimated H-index: 1
(Sichuan Agricultural University)
+ 8 AuthorsDefang Chen11
Estimated H-index: 11
(Sichuan Agricultural University)
Most species of the genus Elizabethkingia are pathogenic to humans and animals, most commonly causing meningitis. However, our understanding of the pathogenic mechanisms involved is poor and there have been few pathological studies of Elizabethkingia spp. in animals. To understand the host injury induced by Elizabethkingia spp., we established a model of E. miricola infection in the black-spotted frog (Pelophylax nigromaculatus). The systematic pathology in and oxidative damage in the infection ...
Published on Sep 17, 2019in Oxidative Medicine and Cellular Longevity4.87
Camille Koffi2
Estimated H-index: 2
(UCA: Université Félix Houphouët-Boigny),
Raffaella Soleti12
Estimated H-index: 12
(University of Angers)
+ 8 AuthorsHenri Die-Kakou2
Estimated H-index: 2
(UCA: Université Félix Houphouët-Boigny)
Despite long traditional utilization and some reports on the antihyperglycemic and antihyperlipidemic action of Cassia siamea, the mechanisms involved have not been investigated yet. Thus, the objective of the present study was to investigate whether and how oral administration of the ethanolic extract of Cassia siamea Lam leaves (LECS) improves glucose and insulin homoeostasis, liver damage, and endothelial dysfunction in an experimental model of type 2 diabetes, the leptin-deficient ob/ob mice...
Published on Sep 17, 2019in Oxidative Medicine and Cellular Longevity4.87
Gloria E. Villalpando-Rodriguez (UM: University of Manitoba), Anna R. Blankstein2
Estimated H-index: 2
(UM: University of Manitoba)
+ 1 AuthorsSpencer B. Gibson42
Estimated H-index: 42
(UM: University of Manitoba)
Ferroptosis is an iron-dependent type of cell death distinct from apoptosis or necrosis characterized by accumulation of reactive oxygen species. The combination of siramesine, a lysosomotropic agent, and lapatinib, a dual tyrosine kinase inhibitor (TKI), synergistically induced cell death in breast cancer cells mediated by ferroptosis. In this study, we showed that this combination of siramesine and lapatinib induces synergistic cell death in glioma cell line U87 and lung adenocarcinoma cell li...
Published on Sep 17, 2019in Oxidative Medicine and Cellular Longevity4.87
Ewa Romuk7
Estimated H-index: 7
(Medical University of Silesia),
Celina Wojciechowska10
Estimated H-index: 10
(Medical University of Silesia)
+ 6 AuthorsPiotr Rozentryt13
Estimated H-index: 13
(Medical University of Silesia)
Background. Abnormalities in the oxidative and antioxidant states causing oxidative stress were both found in heart failure (HF) of various aetiologies and atherosclerosis. Aim of Study. The goals of the study were as follows: comparison of oxidative stress parameters (OSP) in ischaemic cardiomyopathy (ICM) () and nonischaemic cardiomyopathy (nICM) () patients; assessment of the relationships of OSP with functional capacity (NYHA class), maximal oxygen consumption (max.O2), left ventricle ejecti...
Published on Sep 16, 2019in Oxidative Medicine and Cellular Longevity4.87
Robert A. Olek11
Estimated H-index: 11
,
Joanna J. Samulak1
Estimated H-index: 1
+ 4 AuthorsWieslawa Lysiak-Szydlowska1
Estimated H-index: 1
Increased plasma trimethylamine N-oxide (TMAO) levels have been associated with cardiovascular diseases (CVD). L-carnitine induces TMAO elevation in human blood, and thus, it has been suggested as developing atherosclerosis. The aim of this study was to determine the relation between selected markers of oxidative stress and plasma TMAO concentration induced by L-carnitine supplementation for 24 weeks in healthy aged women. Twenty aged women were supplemented during 24 weeks with either 1500 mg L...
Published on Sep 16, 2019in Oxidative Medicine and Cellular Longevity4.87
Dehai Xian3
Estimated H-index: 3
,
Rui Lai2
Estimated H-index: 2
+ 2 AuthorsJianqiao Zhong3
Estimated H-index: 3
Strategies to battle malignant tumors have always been a dynamic research endeavour. Although various vehicles (e.g., chemotherapeutic therapy, radiotherapy, surgical resection, etc.) are used for skin cancer management, they mostly remain unsatisfactory due to the complex mechanism of carcinogenesis. Increasing evidence indicates that redox imbalance and aberrant reactive oxygen species (ROS) are closely implicated in the oncogenesis of skin cancer. When ROS production goes beyond their clearan...
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