Archives of Disease in Childhood
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#1Beatrice BertiH-Index: 1
#2Roberta OnesimoH-Index: 11
Last. Eugenio MercuriH-Index: 74
view all 8 authors...
There has been increasing evidence that hyperglycaemia, hypoglycaemia and other metabolic abnormalities may occur in the severe end of the spectrum of type 1 spinal muscular atrophy (SMA). An increase in alpha cell number in pancreatic islet composition has been described in SMA knockout mice and in patients with type 1 SMA.1 Recent care recommendations suggest that prolonged fasting should be avoided in order to prevent the risk of hypoglycaemia.2 Type 1 children are often underweight, have a r...
#1Genny RaffaeliH-Index: 8
#2Armando Tripodi (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 27
Last. Stefano Ghirardello (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 9
view all 9 authors...
Objective We determined thromboelastographic (TEG) profiles of healthy very low birthweight infants (VLBWIs) of the day of birth and at set intervals during their first month. Design Prospective observational study with blinded clinical and laboratory follow-up. Setting Level III neonatal intensive care unit (June 2015 to June 2018). Patients Consecutive qualifying VLBWIs were enrolled at birth and followed up for 30 days. Interventions and main outcomes measures Laboratory (citrated-native TEG,...
2 CitationsSource
In July of this year, there was an alert issued by the British Association of Perinatal Medicine regarding the safety of Transwarmer mattresses, highlighting the risk of burns if the mattresses are used in conjunction with other heat sources.1 We are aware that some units are considering abandoning the use of Transwarmers because of this. The reason for disseminating an alert at this time is unclear. This is not new information. In 2007, Carmichael et al demonstrated that the temperature at the ...
Objective With inappropriately large facemasks, it is more difficult to create a seal on the face, potentially leading to ineffective ventilation during neonatal stabilisation. We investigated whether commonly available round facemasks are of appropriate size by measuring facial dimensions in near-term and term infants using two-dimensional (2D) and three-dimensional (3D) images. Design Prospective single-centre observational study. Setting Infants born in our centre at 34–41 weeks’ gestation we...
On 20 February 2020, so-called Italian Patient 1 was admitted to the intensive care unit of his local hospital due to a deteriorating clinical condition from SARS-CoV-2/COVID-19 infection. In Italy, COVID-19 originated from a handful of small towns in northern Italy that were swiftly placed into lockdown. Lockdown of Milan, Venice, Rimini and their provinces and neighbouring towns and cities followed on 8 March and the whole of Italy on 9 March, when the ‘#stayhome’ (#iostoacasa) executive order...
Objective Alveolar capillary dysplasia (ACD) is one of the causes of pulmonary hypertension. Its diagnosis is histological but new pathogenetic data have emerged. The aim of this study was to describe a French cohort of patients with ACD to improve the comprehension and the diagnosis of this pathology which is probably underdiagnosed. Methods A retrospective observational study was conducted in French hospitals. Patients born between 2005 and 2017, whose biological samples were sent to the Frenc...
#1Elizabeth S Draper (University of Leicester)H-Index: 41
#2Jennifer Zeitlin (French Institute of Health and Medical Research)H-Index: 45
Last. Samantha Johnson (University of Leicester)H-Index: 38
view all 13 authors...
Objective To determine whether the variation in neurodevelopmental disability rates between populations persists after adjustment for demographic, maternal and infant characteristics for an international very preterm (VPT) birth cohort using a standardised approach to neurodevelopmental assessment at 2 years of age. Design Prospective standardised cohort study. Setting 15 regions in 10 European countries. Patients VPT births: 22+0–31+6 weeks of gestation. Data collection Standardised data collec...
4 CitationsSource
#1Claire RobertsonH-Index: 1
#2George M. Savva (Norwich University)H-Index: 38
Last. Paul A. ClarkeH-Index: 45
view all 9 authors...
Objective To compare rates of necrotising enterocolitis (NEC), late-onset sepsis, and mortality in 5-year epochs before and after implementation of routine daily multistrain probiotics administration in high-risk neonates. Design Single-centre retrospective observational study over the 10-year period from 1 January 2008 to 31 December 2017. Setting Level 3 neonatal intensive care unit (NICU) of the Norfolk and Norwich University Hospital, UK. Patients Preterm neonates at high risk of NEC: admitt...
3 CitationsSource
#1M.J. Vermeulen (EUR: Erasmus University Rotterdam)H-Index: 10
#2Romy Gaillard (EUR: Erasmus University Rotterdam)H-Index: 28
Last. Janine F. Felix (EUR: Erasmus University Rotterdam)H-Index: 43
view all 7 authors...
Objective To determine the combined effect of 60 genetic variants (single nucleotide polymorphisms, SNPs), previously identified as being associated with birth weight, on fetal growth and placental haemodynamics throughout pregnancy. Design Prospective birth cohort (Generation R Study). Setting General multiethnic population. Participants 5374 singleton liveborn children with genome-wide association arrays and fetal growth data. Methods Longitudinal and cross-sectional analyses of a genetic scor...
#1Sílvia Fraga (University of Porto)H-Index: 12
#2Milton Severo (University of Porto)H-Index: 23
Last. Silvia Stringhini (Geneva College)H-Index: 2
view all 9 authors...
Objective Early life adversity has been associated with increased risk of inflammation and inflammation-related diseases in adulthood. This study aimed to examine the association of childhood socioeconomic conditions with chronic low-grade inflammation over adolescence. Methods We used information on 2942 members (1507 girls and 1435 boys) of the EPITeen (Epidemiological Health Investigation of Teenagers in Porto) cohort that was established in 2003 in Porto, Portugal, and included 13-year-old a...
Top fields of study
Intensive care medicine
Diabetes mellitus