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Reproductive Biomedicine Online
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#1Xiaoyan Wan (HUST: Huazhong University of Science and Technology)
#2Xiaomei He (HUST: Huazhong University of Science and Technology)
Last.Honggang Li (HUST: Huazhong University of Science and Technology)H-Index: 7
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Abstract Research question Frequent and mild scrotal heat stress (fmSHS) often occurs in humans. We aimed to determine the impact of fmSHS on natural fertility, the in vitro fertilization–embryo transfer (IVF-ET) process, and the offspring sex ratio. Design Male mice were randomly divided into four groups: no SHS (controls) and those subjected to SHS at 37°C, 39°C, or 41°C for 30 minutes once a week for five consecutive weeks. The testis, epididymis, and sperm quality were assessed to evaluate t...
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ABSTRACT The availability of non-invasive diagnostic tests is an important factor in the renewed interest in adenomyosis, as the disease can now be more accurately mapped in the uterus without a need for hysterectomy. An agreed system for classifying and reporting the condition will enhance our understanding of the disease and is envisaged to enable comparing research studies and treatment outcomes. In this article, we review previous and more recent attempts at producing a taxonomy, especially ...
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#1Yifei Lv (ZJU: Zhejiang University)
#2Liqi Zhang (ZJU: Zhejiang University)
Last.Jun Lin (ZJU: Zhejiang University)H-Index: 8
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Abstract Research Question Endometriosis is characterized by the occurrence of endometrial-like tissue outside the uterus. Collagen triple helix repeat containing-1 (CTHRC1) is known as a tumor promoting factor in several neoplasms. The purposes of this study are to examine the roles of CTHRC1 in the development and progression of endometriosis, and unravel its underlying mechanisms. Design Quantitative Real-Time Polymerase Chain Reaction, Western blot analyses and enzyme-linked immunosorbent as...
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#1Laura Lotz (FAU: University of Erlangen-Nuremberg)H-Index: 11
Last.Ralf Dittrich (FAU: University of Erlangen-Nuremberg)H-Index: 29
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Abstract Research Question Is ovarian tissue cryopreservation for fertility preservation in prepubertal and adolescent girls efficient, safe and who would benefit most from the procedure? Design Survey and retrospective study including patients, who had ovarian tissue cryopreservation (OTC) under the age of 18 years in a single centre for fertility preservation. Serum AMH levels were measured as a marker for detection of a diminished ovarian reserve. Results 53 from 102 women participated in the...
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#1Xiaojie Zhou (UCSF: University of California, San Francisco)
#2Dana B. McQueen (NU: Northwestern University)H-Index: 4
Last.Eve C. Feinberg (NU: Northwestern University)H-Index: 10
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ABSTRACT Research Question Is minority race associated with worse oocyte donation outcomes? Design Retrospective analysis of 926 oocyte recipients who underwent a donor cycle with fresh embryo transfer at a single fertility center between January 2009 to June 2015. Race was self-reported. To adjust for repeat donors within the sample, mixed models were used to analyze donor parameters and recipient outcomes. The recipient outcome models were adjusted for age, body mass index and primary infertil...
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#2Sylvie Manouvrier-Hanu (Lille University of Science and Technology)H-Index: 2
Last.Sophie Catteau-Jonard (Lille University of Science and Technology)H-Index: 19
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ABSTRACT Research question: Primary ovarian insufficiency (POI) is defined as the early exhaustion of ovarian function, before the age of 40 years. Its origin is genetic in 20 to 25% of cases. Unusually, sequence variants of the NR5A1/SF-1 gene may result in POI, or various disorders of gonadal development (DGD), or adrenal insufficiency. Design: We describe the cases of two families in which the association of DGD and POI enabled a diagnosis of NR5A1 deleterious variations. Their clinical, horm...
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#1Marianne Watters (Glas.: University of Glasgow)
Last.Scott M. Nelson (Glas.: University of Glasgow)H-Index: 51
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Abstract This review and meta-analysis aims to assess the effect of prolonged progesterone support on pregnancy outcomes in women undergoing a fresh embryo transfer after IVF/ICSI. Two independent reviewers searched EMBASE, MEDLINE and grey literature from inception to January 2019 for RCTs of prolonged progesterone support vs early cessation. Risk of bias was assessed. Outcome measures were live birth, miscarriage and ongoing pregnancy rate. Study protocol CRD42018088605. Seven trials involving...
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#1Meritxell Jodar (University of Barcelona)H-Index: 10
#2Claudio Attardo-Parrinello (University of Barcelona)
Last.Rafael Oliva (University of Barcelona)H-Index: 44
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Abstract Research Question Do alterations of human sperm protein profile affect embryo quality? Design The sperm proteins from 27 infertile couples undergoing ICSI were extracted and digested. The resulting peptides were labeled using tandem mass tags (TMT), separated by two-dimensional liquid chromatography (2D-LC), and identified and quantified using tandem mass spectrometry (MS/MS). Subsequently, sperm protein and peptide abundance were correlated with the quality of the ICSI-derived embryos ...
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#1Stefanie De Gheselle (Ghent University Hospital)H-Index: 4
#2Paul De Sutter (Ghent University Hospital)H-Index: 49
Last.Kelly Tilleman (Ghent University Hospital)H-Index: 15
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ABSTRACT Research question Is there a difference in blastocyst formation between fresh and vitrified-warmed sibling oocytes and can this difference be attributed to changes in embryo morphokinetics? Design Between February 2016-December 2017, 472 MII oocytes from 67 donor cycles from 27 different healthy anonymous oocyte donors were allocated for fresh transfer (FO)(n=220) to a synchronous recipient or vitrified (VITO)(n=252) to be warmed and transferred to another recipient. Embryos derived fro...
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Top fields of study
Obstetrics
Endocrinology
Andrology
Embryo
Pregnancy
Biology