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Epilepsia
IF
5.56
Papers
12828
Papers 13072
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#1Lili Long (CSU: Central South University)H-Index: 9
#2Marian Galovic (UZH: University of Zurich)
Last. Matthias J. KoeppH-Index: 44
view all 11 authors...
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#1Nico A. Jansen (LUMC: Leiden University Medical Center)H-Index: 1
#2Anisa Dehghani (LUMC: Leiden University Medical Center)H-Index: 1
Last. Arn M. J. M. van den Maagdenberg (LUMC: Leiden University Medical Center)H-Index: 55
view all 5 authors...
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#1Donald W. Mann (Pfizer)H-Index: 8
#2Jeremias Antinew (Pfizer)H-Index: 1
view all 14 authors...
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OBJECTIVE: Through international collaboration, we evaluated the phenotypic aspects of a multiethnic cohort of KCNT1-related epilepsy and explored genotype-phenotype correlations associated with frequently encountered variants. METHODS: A cross-sectional analysis of children harboring pathogenic or likely pathogenic KCNT1 variants was completed. Children with one of the two more common recurrent KCNT1 variants were compared with the rest of the cohort for the presence of particular characteristi...
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#1Nicola Specchio (Boston Children's Hospital)H-Index: 31
#2Nicola Pietrafusa (Boston Children's Hospital)H-Index: 5
Last. Federico Vigevano (Boston Children's Hospital)H-Index: 42
view all 5 authors...
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#1Lynette G. Sadleir (University of Otago)H-Index: 24
#2Guillem de Valles‐Ibáñez (University of Otago)
Last. Melanie Bahlo (University of Melbourne)H-Index: 45
view all 13 authors...
Variants in RORB have been reported in eight individuals with epilepsy, with phenotypes ranging from eyelid myoclonia with absence epilepsy to developmental and epileptic encephalopathies. We identified novel RORB variants in 11 affected individuals from four families. One was from whole genome sequencing and three were from RORB screening of three epilepsy cohorts: developmental and epileptic encephalopathies (n = 1021), overlap of generalized and occipital epilepsy (n = 84), and photosensitivi...
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#1Céline Thibault (Children's Hospital of Philadelphia)
#2Maryam Y. Naim (Children's Hospital of Philadelphia)H-Index: 17
Last. Shavonne L. Massey (Children's Hospital of Philadelphia)H-Index: 7
view all 7 authors...
OBJECTIVE: To compare the safety and efficacy of phenobarbital and levetiracetam in a cohort of neonates with seizures following cardiac surgery. METHODS: We performed a retrospective single-center study of consecutive neonates with electrographically confirmed seizures managed with antiseizure medication after cardiac surgery from June 15, 2012 to December 31, 2018. We compared the safety and efficacy of phenobarbital and levetiracetam as first-line therapy. RESULTS: First-line therapy was phen...
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#1Sun Ah Choi (DU: Dankook University)
#2Hunmin Kim (Seoul National University Bundang Hospital)H-Index: 11
Last. Ki Joong Kim (SNU: Seoul National University)H-Index: 22
view all 8 authors...
OBJECTIVE: Antiseizure drugs (ASDs) are known to cause a wide range of adverse drug reactions (ADRs). Recently, electronic health care data using the common data model (CDM) have been introduced and commonly adopted in pharmacovigilance research. We aimed to analyze ASD-related ADRs using CDM and to assess the feasibility of CDM analysis in monitoring ADR in a single tertiary hospital. METHODS: We selected five ASDs: oxcarbazepine (OXC), lamotrigine (LTG), levetiracetam (LEV), valproic acid (VPA...
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#1Kathrin Wagner (University of Freiburg)H-Index: 20
#2Karin Gau (University of Freiburg)
Last. Jürgen Beck (University of Freiburg)H-Index: 38
view all 15 authors...
OBJECTIVE: In patients with temporal lobe epilepsy (TLE) with a nonlesional and nonepileptogenic hippocampus (HC), in order to preserve functionally intact brain tissue, the HC is not resected. However, some patients experience postoperative memory decline, possibly due to disruption of the extrahippocampal memory network and secondary hippocampal volume (HV) loss. The purpose of this study was to determine the extent of hippocampal atrophy ipsilateral and contralateral to the side of the surger...
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#1Kaat Vandecasteele (Katholieke Universiteit Leuven)H-Index: 1
#2Thomas De Cooman (Katholieke Universiteit Leuven)H-Index: 5
Last. Wim Van Paesschen (Katholieke Universiteit Leuven)H-Index: 40
view all 7 authors...
OBJECTIVE: Seizure diaries kept by patients are unreliable. Automated electroencephalography (EEG)-based seizure detection systems are a useful support tool to objectively detect and register seizures during long-term video-EEG recording. However, this standard full scalp-EEG recording setup is of limited use outside the hospital, and a discreet, wearable device is needed for capturing seizures in the home setting. We are developing a wearable device that records EEG with behind-the-ear electrod...
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Top fields of study
Psychiatry
Epilepsy
Anesthesia
Electroencephalography
Medicine