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Veterinary Immunology and Immunopathology
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#1Keisuke Konishi (Rakuno Gakuen University)
#2Hirotaka Igarashi (Azabu University)H-Index: 8
Last.Koichi Ohno (UTokyo: University of Tokyo)H-Index: 36
view all 9 authors...
Abstract Inflammatory colorectal polyp (ICRP) is an emerging disease in Miniature Dachshunds (MDs). Animals with this disease exhibit multiple polyps with severe neutrophil infiltration that respond to immunosuppressive therapy. Macrophages in polypoid lesions have been described to play an important role in neutrophil infiltration in the lesion by producing IL-8. In contrast, IL-10, an anti-inflammatory cytokine, was also reported to be upregulated in polypoid lesions, but its significance in t...
#1Brian A. DiGangi (UF: University of Florida)H-Index: 5
#2Patricia A. Dingman (UF: University of Florida)H-Index: 5
Last.Ramiro Isaza (UF: University of Florida)H-Index: 18
view all 6 authors...
Abstract The purpose of this study was to estimate the apparent prevalence and identify risk factors for antibody levels (AL) against canine distemper virus (CDV), canine parvovirus (CPV), and canine adenovirus (CAV) in three communities in the metropolitan area of Quito, Ecuador that have limited access to regular veterinary care. Whole blood samples were collected from 154 dogs presenting to three veterinary field clinics in mainland Ecuador and tested for AL against CDV, CPV, and CAV by a com...
#1Nattinee Kittiwan (CMU: Chiang Mai University)H-Index: 1
#2Panuwat Yamsakul (CMU: Chiang Mai University)H-Index: 3
Last.Prapas Patchanee (CMU: Chiang Mai University)H-Index: 9
view all 7 authors...
Abstract Porcine reproductive and respiratory syndrome (PRRS), caused by the PRRS virus (PRRSV), remains a major economic threat to swine production throughout the world. The aim of this study was to investigate the humoral and cell-mediated immune responses to PRRSV in 10 PRRSV vaccinated and 10 non-vaccinated young pigs obtained from a PRRSV-seropositive herd under field conditions. On day 35 days of post-vaccination (dpv), two PRRSV seropositive mixed-litter pigs were added to each group to c...
#1Joana N.R. Dias (University of Lisbon)H-Index: 1
#2Mariana Lopes (University of Lisbon)
Last.Solange Gil (University of Lisbon)H-Index: 8
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Abstract Non-Hodgkin Lymphoma (NHL) is among the most common neoplasias in dogs and humans. Owing to remarkable similarities with its human counterpart, the canine lymphoma (cNHL) model has been proposed as a powerful framework for rapid and clinically relevant translation of novel immunotherapies. However, the establishment of cNHL as a predictive preclinical model has been hampered by the limited characterization of the canine immune system. Cytokines are key players of the interaction between...
#1Alison V. Lee (U of G: University of Guelph)H-Index: 1
#2Lan You (U of G: University of Guelph)H-Index: 1
Last.N.A. Karrow (U of G: University of Guelph)H-Index: 2
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Abstract Maternal stress, such as a bacterial infection occurring in late gestation, may predispose offspring to a variety of diseases later in life. It may also alter programming of developing systems within the fetus, such as the hypothalamic-pituitary-adrenal (HPA) axis and immune system. Dietary supplementation during the last trimester of pregnancy with immune-modulating compounds may be a means of reducing potential adverse effects of maternal stress on the developing fetus. Essential omeg...
#1Maria K. Arendt (UW: University of Wisconsin-Madison)H-Index: 2
#2Jonathan Elissa (UW: University of Wisconsin-Madison)
Last.Laura J. Knoll (UW: University of Wisconsin-Madison)H-Index: 15
view all 7 authors...
Abstract Eimeria species are intestinal protozoan parasites that cause lack of production, malabsorption and mortality in floor raised chickens. Administering an oral antibody to interleukin 10 (aIL-10) reduces the symptoms of coccidiosis in broilers, indicating interleukin 10 (IL-10) is key to Eimeria pathology. IL-10 is an anti-inflammatory cytokine and acts as a stand down signal to reduce inflammation and host pathology during disease. Related protozoan parasites exploit IL-10 to reduce path...
#2Berend J. Bosch (UU: Utrecht University)H-Index: 1
Last.Wolfgang BaumgärtnerH-Index: 34
view all 8 authors...
Abstract Middle East respiratory syndrome (MERS) represents an important respiratory disease accompanied by lethal outcome in one third of human patients. In recent years, several investigators developed protective antibodies which could be used as prophylaxis in prospective human epidemics. In the current study, eight human monoclonal antibodies (mAbs) with neutralizing and non-neutralizing capabilities, directed against different epitopes of the MERS-coronavirus (MERS-CoV) spike (MERS-S) prote...
#1Emily J. Aston (UGA: University of Georgia)H-Index: 1
#2Mark W. Jackwood (UGA: University of Georgia)H-Index: 32
Last.Brian J. Jordan (UGA: University of Georgia)H-Index: 7
view all 10 authors...
Abstract Commercial broilers are commonly exposed to gaseous ammonia (NH3) originating from degradation of nitrogen-containing excreta in the litter during the grow-out period. Ammonia concentrations in the air are higher in poorly ventilated houses and appear to coincide with the elevated incidence of respiratory disease occurring during the winter months. This study examined the effect of NH3 on the immune response to infectious bronchitis virus (IBV) vaccination and protection against homolog...
#1Netanya Bernitz (South African Medical Research Council)
#2Tanya J. Kerr (South African Medical Research Council)
Last.Sven D.C. Parsons (South African Medical Research Council)H-Index: 13
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Abstract The cytokine interferon gamma-inducible protein 10 (IP-10) is a sensitive biomarker of Mycobacterium bovis (M. bovis) infection in African buffaloes (Syncerus caffer). However, elevated levels of IP-10 in QuantiFERON®-TB Gold (QFT) unstimulated whole blood compromises the utility of this biomarker. In this study, IP-10 and interferon gamma (IFN-γ) concentrations in whole blood samples from M. bovis culture-confirmed buffaloes with varying degrees of pathological changes (n = 72) and uni...
#1J. Whitney (USYD: University of Sydney)H-Index: 3
#2Bianca Haase (USYD: University of Sydney)H-Index: 17
Last.Vanessa R. Barrs (USYD: University of Sydney)H-Index: 25
view all 4 authors...
Abstract Fungal species in the genus Aspergillus are environmental saprophytes that can act as opportunistic pathogens of the nasal cavity and paranasal sinuses in humans, cats and other species. Upper respiratory tract aspergillosis (URTA) presents as non-invasive and invasive forms with the latter occurring almost exclusively in immunocompromised hosts. However, in domestic cats, invasive URTA affects apparently immunocompetent patients. A defect in innate immunity has been proposed as a predi...
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