European Journal of Nuclear Medicine and Molecular Imaging
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#1Pauline T. Lukey (GSK: GlaxoSmithKline)H-Index: 24
#2Christopher CoelloH-Index: 8
Last. Richard P. Marshall (GSK: GlaxoSmithKline)H-Index: 27
view all 20 authors...
Purpose The RGD-integrin, αvβ6, plays a role in the pathogenesis of pulmonary fibrosis through activation of transforming growth factor beta (TGFβ). This study sought to quantify expression of αvβ6 in the lungs of healthy humans and subjects with pulmonary fibrosis using the αvβ6-selective [18F]FB-A20FMDV2 PET ligand.
#1Lisa Bodei (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 10
#2Mark KiddH-Index: 46
Last. Irvin M. Modlin (Yale University)H-Index: 61
view all 12 authors...
Purpose Peptide receptor radionuclide therapy (PRRT) is effective for metastatic/inoperable neuroendocrine tumors (NETs). Imaging response assessment is usually efficient subsequent to treatment completion. Blood biomarkers such as PRRT Predictive Quotient (PPQ) and NETest are effective in real-time. PPQ predicts PRRT efficacy; NETest monitors disease. We prospectively evaluated: (1) NETest as a surrogate biomarker for RECIST; (2) the correlation of NETest levels with PPQ prediction.
#1Harun Ilhan (LMU: Ludwig Maximilian University of Munich)H-Index: 12
#2Simon Lindner (LMU: Ludwig Maximilian University of Munich)H-Index: 10
Last. Peter Bartenstein (LMU: Ludwig Maximilian University of Munich)H-Index: 55
view all 16 authors...
Introduction PET/CT using 68Ga-labeled somatostatin analogs (SSA) targeting somatostatin receptors (SSR) on the cell surface of well-differentiated neuroendocrine tumors (NET) represents the clinical reference standard for imaging. However, economic and logistic challenges of the 68Ge/68Ga generator-based approach have disadvantages over 18F-labeled compounds. Here, we present the first in-human data of 18F-SiFAlin-TATE, a novel 18F-labeled, SSR-targeting peptide. The aim was to compare the intr...
#1Sayak Choudhury (ACTREC: Tata Memorial Hospital)H-Index: 1
#2Archi Agrawal (ACTREC: Tata Memorial Hospital)H-Index: 9
Last. Venkatesh Rangarajan (ACTREC: Tata Memorial Hospital)H-Index: 15
view all 8 authors...
#1Maarten L. J. Smits (UU: Utrecht University)H-Index: 12
#2Mathijs G. Dassen (UU: Utrecht University)H-Index: 1
Last. Marnix G. E. H. Lam (UU: Utrecht University)H-Index: 24
view all 8 authors...
Purpose As an alternative to technetium-99m-macroaggregated albumin (99mTc-MAA), a scout dose of holmium-166 (166Ho) microspheres can be used prior to 166Ho-radioembolization. The use of identical particles for pre-treatment and treatment procedures may improve the predictive value of pre-treatment analysis of distribution. The aim of this study was to analyze the agreement between 166Ho-scout and 166Ho-therapeutic dose in comparison with the agreement between 99mTc-MAA and 166Ho-therapeutic dos...
1 CitationsSource
Introduction The aim of this study is to determine whether 99mTc-MAA SPECT/CT-based dosimetry could predict the actual absorbed dose in hepatocellular carcinoma (HCC) or liver metastases, treated by glass or resin microspheres.
1 CitationsSource
Purpose One-third of patients with RAS wild-type mCRC do not benefit from anti-EGFR monoclonal antibodies. This might be a result of variable pharmacokinetics and insufficient tumor targeting. We evaluated cetuximab tumor accumulation on [89Zr]Zr-cetuximab PET/CT as a potential predictive biomarker and determinant for an escalating dosing strategy.
#1Divya Yadav (AIIMS: All India Institute of Medical Sciences)
#2Sanjana Ballal (AIIMS: All India Institute of Medical Sciences)H-Index: 7
Last. Chandrasekhar Bal (AIIMS: All India Institute of Medical Sciences)H-Index: 25
view all 6 authors...
Purpose Recently, the new hybrid chelator DATA (6-amino-1,4-diazepine-triacetate) has been introduced, which has the advantage of high yield and radiolabelling of DATA-based octreotide derivative (TOC) at room temperature in contrast to tetraazacyclododecane-1,4,7,10-tetraacetate (DOTA) that needs 95 °C for effective labelling. However, the diagnostic potential of DATA-TOC has not been studied with other chelators in humans. The aim of this study was to compare the diagnostic efficacy of [68Ga]G...
#1Yan Li (University of Duisburg-Essen)H-Index: 1
#2Benedikt Michael Schaarschmidt (University of Duisburg-Essen)H-Index: 12
Last. LanghorstJost (University of Duisburg-Essen)H-Index: 40
view all 11 authors...
Purpose To evaluate the diagnostic performance of PET-MR enterography in detecting histological active inflammation in patients with ulcerative colitis and the impact of bowel purgation on diagnostic accuracies of PET-MR parameters.
Top fields of study
Positron emission tomography
Nuclear medicine