BMC Medical Research Methodology
Papers 2038
1 page of 204 pages (2,038 results)
Trainee research collaboratives (TRCs) have pioneered high quality, prospective ‘snap-shot’ surgical cohort studies in the UK. Outcomes After Kidney injury in Surgery (OAKS) was the first TRC cohort study to attempt to collect one-year follow-up data. The aims of this study were to evaluate one-year follow-up and data completion rates, and to identify factors associated with improved follow-up rates. In this multicentre study, patients undergoing major gastrointestinal surgery were prospectively...
#1Yimin Chen (SYSU: Sun Yat-sen University)
#2Jialing Huang (SYSU: Sun Yat-sen University)
Last.Jinxin Zhang (SYSU: Sun Yat-sen University)
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In clinical and epidemiological researches, continuous predictors are often discretized into categorical variables for classification of patients. When the relationship between a continuous predictor and log relative hazards is U-shaped in survival data, there is a lack of a satisfying solution to find optimal cut-points to discretize the continuous predictor. In this study, we propose a novel approach named optimal equal-HR method to discretize a continuous variable that has a U-shaped relation...
#1Helen Eke (University of Exeter)H-Index: 2
#2Astrid Janssens (University of Exeter)H-Index: 12
Last.Tamsin Ford (University of Exeter)H-Index: 43
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Health services have not provided adequate support for young people with long term health conditions to transfer from child to adult services. National Institute of Health and Care (NICE) guidance on transition has been issued to address these gaps. However, data are often sparse about the number of young adults who might need to transition. Using Attention Deficit Hyperactivity Disorder (ADHD) as an exemplar, this study used an existing surveillance system and a case note review to capture the ...
#1Michael Robinson (UWO: University of Western Ontario)
#2Andrew M. Johnson (UWO: University of Western Ontario)H-Index: 29
Last.Joy C. MacDermid (McMaster University)H-Index: 63
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Patient-reported outcome measures developed using Classical Test Theory are commonly comprised of ordinal level items on a Likert response scale are problematic as they do not permit the results to be compared between patients. Rasch analysis provides a solution to overcome this by evaluating the measurement characteristics of the rating scales using probability estimates. This is typically achieved using commercial software dedicated to Rasch analysis however, it is possible to conduct this ana...
#1Therese M.-L. Andersson (KI: Karolinska Institutet)H-Index: 27
#2Mark J. Rutherford (University of Leicester)H-Index: 11
Last.Paul C. Lambert (KI: Karolinska Institutet)H-Index: 44
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Background The life expectancy of cancer patients, and the loss in expectation of life as compared to the life expectancy without cancer, is a useful measure of cancer patient survival and complement the more commonly reported 5-year survival. The estimation of life expectancy and loss in expectation of life generally requires extrapolation of the survival function, since the follow-up is not long enough for the survival function to reach 0. We have previously shown that the survival of the canc...
Last.Livia Puljak (CUA: The Catholic University of America)H-Index: 15
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Background Reporting quality of systematic reviews’ (SRs) abstracts is important because this is often the only information about a study that readers have. The aim of this study was to assess adherence of SR abstracts in the field of anesthesiology with the reporting checklist PRISMA extension for Abstracts (PRISMA-A) and to analyze to what extent will the use of PRISMA-A yield concordant ratings in two raters without prior experience with the checklist.
#1Naomi C. Brownstein (FSU: Florida State University)H-Index: 9
#2Jianwen Cai (UNC: University of North Carolina at Chapel Hill)H-Index: 15
Background Many epidemiological studies test trends when investigating the association between a risk factor and a disease outcome. Continuous exposures are commonly discretized when the outcome is nonlinearly related to exposure as well as to facilitate interpretation and reduce measurement error. Guidance is needed regarding statistically valid trend tests for epidemiological data of this nature.
#2Ali Mahmoud Ahmed (Al-Azhar University)H-Index: 7
Last.Nguyen Tien Huy (Ton Duc Thang University)H-Index: 19
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Background The quality of systematic reviews and meta-analyses (SR/MAs) depends on the extent of the methods used. We investigated the methodological steps used by authors of SR/MAs of clinical trials via an author survey.
#2Therese M.-L. Andersson (KI: Karolinska Institutet)H-Index: 27
Last.Martin BøgstedH-Index: 17
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Background Within cancer care, dynamic evaluations of the loss in expectation of life provides useful information to patients as well as physicians. The loss of lifetime function yields the conditional loss in expectation of life given survival up to a specific time point. Due to the inevitable censoring in time-to-event data, loss of lifetime estimation requires extrapolation of both the patient and general population survival function. In this context, the accuracy of different extrapolation a...
#1Juste Aristide Goungounga (AMU: Aix-Marseille University)H-Index: 1
#2Célia Touraine (AMU: Aix-Marseille University)
Last.Roch Giorgi (AMU: Aix-Marseille University)H-Index: 36
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Background Net survival, a measure of the survival where the patients would only die from the cancer under study, may be compared between treatment groups using either “cause-specific methods”, when the causes of death are known and accurate, or “population-based methods”, when the causes are missing or inaccurate. The latter methods rely on the assumption that mortality due to other causes than cancer is the same as the expected mortality in the general population with same demographic characte...
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Randomized controlled trial
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