Journal of Developmental Origins of Health and Disease
Papers 791
1 page of 80 pages (791 results)
#1D. Samaranayake (UoC: University of Colombo)
#2Pulani Lanerolle (UoC: University of Colombo)H-Index: 6
Last. Vithanage Pujitha Wickramasinghe (UoC: University of Colombo)H-Index: 10
view all 7 authors...
Early growth pattern is increasingly recognized as a determinant of later obesity. This study aimed to identify the association between weight gain in early life and anthropometry, adiposity, leptin, and fasting insulin levels in adolescence. A cross-sectional study was conducted in 366 school children aged 11-13 years. Weight, height, and waist circumference (WC) were measured. Fat mass (FM) was assessed using bioelectrical impedance analysis. Blood was drawn after a 12-h fast for insulin and l...
#1Livia Prometti de Rezende (UFU: Federal University of Uberlandia)
#2Jessica Fortunato Silva (UFU: Federal University of Uberlandia)
Last. A. P C Balbi (UFU: Federal University of Uberlandia)H-Index: 2
view all 5 authors...
Alterations in the maternal environment may impact on the fetal development. The objective of this study was to investigate the gastrointestinal consequences of maternal hypothyroidism for the male offspring from Wistar rats. The pregnant rats were divided into three groups: control (C - received water), experimental 1 [E1 - received methimazole (MMI) solution] during gestation and lactation, and experimental 2 (E2 - received MMI solution) during gestation. Maternal parameters evaluated: free T3...
Maternal undernutrition decreases sperm production in male offspring, possibly through insulin-like growth factor (IGF-I). To test this hypothesis, we fed pregnant Wistar rats ad libitum with a standard diet (CONTROL) or fed 50% of CONTROL intake, either throughout pregnancy (UNP), lactation (UNL, or both (UNPL). After weaning, male offspring (n = 10 per treatment) were fed a standard diet until postnatal day 160, when testes process for histological and molecular analyses. IGF-I immunostaining ...
#1Emilie M. Herzog (EUR: Erasmus University Rotterdam)H-Index: 4
#2Alex J. Eggink (EUR: Erasmus University Rotterdam)H-Index: 15
Last. Régine P.M. Steegers-Theunissen (EUR: Erasmus University Rotterdam)H-Index: 58
view all 10 authors...
Epigenetic programming is essential for lineage differentiation, embryogenesis and placentation in early pregnancy. In epigenetic association studies, DNA methylation is often examined in DNA derived from white blood cells, although its validity to other tissues of interest remains questionable. Therefore, we investigated the tissue specificity of epigenome-wide DNA methylation in newborn and placental tissues. Umbilical cord white blood cells (UC-WBC, n = 25), umbilical cord blood mononuclear c...
#1Mari S. Oba (Toho University)H-Index: 9
#2Yoshitaka Murakami (Toho University)H-Index: 17
view all 10 authors...
Low gestational weight gain (GWG) is a known risk factor of low birthweight. Although studies have previously examined the associations between GWG and birthweight, the period-specific effects of low GWG in each trimester remain unclear. This study aimed to quantify the trimester-specific direct effects of low GWG in Japanese women on birthweight. Using perinatal data from a cohort study, we analyzed pregnant women delivered at an obstetrics/gynecology hospital between October 2006 and May 2010....
Clinical and experimental studies show an association between maternal periodontitis and adverse outcomes during gestation. On the other hand, there were no studies evaluating the impact of maternal periodontitis on the offspring. Thus, our objective was to investigate the repercussion of maternal periodontitis on the development of asthma in the offspring. Pregnant rats were submitted or not to periodontitis by ligature technique. Thirty days after birth, the puppies were sensitized and challen...
#1Siobhan Tu'akoi (University of Auckland)H-Index: 1
#2Mark H. Vickers (University of Auckland)H-Index: 37
Last. Jacquie L. Bay (University of Auckland)H-Index: 4
view all 3 authors...
Low non-communicable diseases (NCDs), accounting for more than 80% of NCD-related deaths globally. Research into early-life influences on these diseases via the developmental origins of health and disease (DOHaD) paradigm has informed health promotion interventions and policies focused on optimising early-life health. However, little is known about where this research occurs and whether it reaches and reflects the countries most affected by NCDs. This review searched for DOHaD studies that inves...
#1Ruth Walker (Monash University, Clayton campus)H-Index: 4
#2Sheila Drakeley (UNC: University of North Carolina at Chapel Hill)
Last. Jacqueline Boyle (Monash University, Clayton campus)H-Index: 18
view all 8 authors...
A preconception Virtual Patient Advocate (VPA) called "Gabby" supported African-American women to decrease their preconception health risks and may be a scalable resource to increase women's access to preconception care. Aims were to assess the acceptability of a preconception VPA in women living in Australia and document the changes required to adapt Gabby to suit an Australian context. Taking a descriptive qualitative approach, nonpregnant female participants (n = 31), aged 18-45 years, living...
Top fields of study
Diabetes mellitus