Annals of Surgical Oncology
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#1S. Lof (University of Southampton)H-Index: 1
#1Sanne LofH-Index: 2
Last. M. Abu HilalH-Index: 22
view all 19 authors...
Background: Several studies have suggested a survival benefit of neoadjuvant therapy (NAT) for pancreatic ductal adenocarcinoma (PDAC) in the pancreatic head. Data concerning NAT for PDAC located in pancreatic body or tail are lacking. Methods: Post hoc analysis of an international multicenter retrospective cohort of distal pancreatectomy for PDAC in 34 centers from 11 countries (2007–2015). Patients who underwent resection after NAT were matched (1:1 ratio), using propensity scores based on bas...
#1Jonas A. Nelson (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 22
#2Nikhil Sobti (MSK: Memorial Sloan Kettering Cancer Center)
Last. Robert J. Allen (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 2
view all 11 authors...
Background Obesity is a significant public health concern and clear risk factor for complications following breast reconstruction. To date, few have assessed patient-reported outcomes (PROs) focused on this key determinant.
#1Luka Flegar (TUD: Dresden University of Technology)H-Index: 1
#2C. Groeben (TUD: Dresden University of Technology)H-Index: 5
Last. Johannes Huber (TUD: Dresden University of Technology)H-Index: 11
view all 8 authors...
Background Nephron-sparing surgery (NSS) is the treatment of choice for T1 renal tumors. This study compared the implementation of NSS in the United States and Germany.
1 CitationsSource
#1Cong Wang (SDU: Shandong University)H-Index: 7
Last. Ming Lu
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PURPOSE: The benefit of adjuvant chemotherapy remains unknown for patients with stage IA micropapillary predominant (MPP) lung adenocarcinoma (ADC). This study investigated the effect of adjuvant chemotherapy in ADC and MPP patients in stage IA. METHODS: A total of 5220 stage IA lung ADC patients from SEER database and 152 MPP subtype patients from Qilu Hospital of Shandong University were retrospectively analyzed. Propensity score matching analysis was used to adjust the confounding factors. Th...
#1Abhineet UppalH-Index: 2
#2Stacey L. SternH-Index: 24
Last. Mark B. Faries (Cedars-Sinai Medical Center)H-Index: 33
view all 17 authors...
Recommended treatment for patients with sentinel lymph node (SLN)-positive melanoma has recently changed. Randomized trials demonstrated equivalent survival with close observation versus completion lymph node dissection (CLND), but increased regional node recurrence. We evaluated factors related to in-basin nodal recurrence after lymphadenectomy (LND) for SLN-positive or macroscopic nodal metastases. An institutional database and the first Multicenter Selective Lymphadenectomy Trial (MSLT-I) wer...
#1Yiliang Zhang (Fudan University)H-Index: 14
#2Guodong Li (Fudan University)H-Index: 7
Last. Haiquan Chen (Fudan University)H-Index: 33
view all 13 authors...
Background The tumor-node-metastasis classification system has proposed that lung cancers presenting as multifocal ground-glass nodules (multi-GGN) on computed tomography scan should be staged as multiple primaries instead of intrapulmonary metastases. However, the problem still exists for those synchronous multiple lung adenocarcinomas (SMLA) involving solid lesions. This study aimed to explore the distinct features of SMLA to better define the diagnosis and staging of this disease.
PURPOSE: This study was designed to examine facility-level variation in the extent of pelvic lymphadenectomy and to determine whether more extensive lymphadenectomy is associated with a survival benefit among men with localized high-risk prostate cancer. METHODS: Using data from the National Cancer Data Base, we identified 13,652 men with a high predicted probability of 10-year survival ( /= 17 lymph nodes), respectively. Extended lymphadenectomy was not associated with a survival benefit relati...
#1Wen-Chin Chiu (KMU: Kaohsiung Medical University)H-Index: 3
#2Pen-Tzu Fang (KMU: Kaohsiung Medical University)H-Index: 1
Last. Shyng-Shiou F. YuanH-Index: 18
view all 11 authors...
Background Rad51 is a protein which plays a vital role in DNA double-strand break repair and maintenance of telomeres. However, the underlying mechanism for its action in esophageal squamous cell carcinoma (ESCC) remains unclear.
#2Steven Forsythe (Wake Forest Institute for Regenerative Medicine)H-Index: 5
Last. Aleksander SkardalH-Index: 22
view all 9 authors...
We hypothesized that engineering a combined lymph node/melanoma organoid from the same patient would allow tumor, stroma, and immune system to remain viable for personalized immunotherapy screening. Surgically obtained matched melanoma and lymph node biospecimens from the same patient were transferred to the laboratory and washed with saline, antibiotic, and red blood cell lysis buffer. Biospecimens were dissociated, incorporated into an extracellular matrix (ECM)-based hydrogel system, and biof...
2 CitationsSource
#1Fumihiko Kinoshita (Kyushu University)H-Index: 4
#2Kazuki Takada (Kyushu University)H-Index: 9
Last. Masaki Mori (Kyushu University)H-Index: 88
view all 14 authors...
Background Immunotherapy has become a standard treatment option for non-small cell lung cancer (NSCLC), with the tumor microenvironment attracting significant attention. CD8 + and forkhead box protein P3 + (FoxP3 +) tumor-infiltrating lymphocytes (TILs) influence the tumor microenvironment, but the clinical significance of CD8 + and FoxP3 + TILs in stage IA lung adenocarcinoma (LAD) is poorly understood.
Top fields of study
Surgical oncology
Breast cancer
General surgery