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Cardiology in Review
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#1Grace ShyhH-Index: 1
#2James J. NawarskasH-Index: 17
Last. Angela Cheng-LaiH-Index: 10
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Each year 790,000 people in the United States suffer from a myocardial infarction. This results in the permanent loss of cardiomyocytes and an irreversible loss of cardiac function. Current therapies lower mortality rates, but do not address the core pathology, which opens a pathway to step-wise heart failure. Utilizing stem cells to regenerate the dead tissue is a potential method to reverse these devastating effects. Several clinical trials have already demonstrated the safety of stem cell the...
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#1Aaqib H. Malik (NYMC: New York Medical College)H-Index: 2
#1Aaqib H. MalikH-Index: 1
Last. Wilbert S. AronowH-Index: 64
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Diabetes mellitus (DM) and chronic kidney disease (CKD) significantly increase the risk of cardiovascular morbidity and mortality. Sodium-glucose cotransporter-2 (SGLT-2) inhibitors are a new class of hypoglycemic agents that have shown significant promise in the reduction of cardiovascular events. Current guideline recommendations do not support the use of these agents in patients with CKD stage 3 or higher. We performed a comprehensive meta-analysis to evaluate their cardiovascular effects in ...
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Acute occlusion of the abdominal aorta is a catastrophic occurrence that results in high risk of limb loss and death. The etiology has historically been either acute embolism obstructing the aortic bifurcation in 8-75% of patients, or thrombosis of existing aorta-iliac occlusive disease in 35-84% of patients. Other etiologies include thrombosis of either a previously-placed endograft or aortic graft or acute dissection. The most common symptoms are severe pain in almost 100% of patients, or lowe...
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#1Filipe Ferrari (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 1
#2Anderson Donelli da Silveira (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 5
Last. Ricardo Stein (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 27
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Atrial fibrillation (AF) is considered the most common sustained cardiac arrhythmia, and it is associated with a significant risk of adverse events, especially ischemic stroke. Oral anticoagulation is the cornerstone for stroke prevention in AF; for many years, only vitamin K antagonists were used for this purpose, with an absolute risk reduction >60% for. However, these agents have limitations, such as narrow therapeutic margins and drug-food and drug-drug interactions. More recently, four dire...
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#1Srikanth Yandrapalli (NYMC: New York Medical College)H-Index: 6
#2Aaqib H. Malik (NYMC: New York Medical College)H-Index: 2
Last. William H. Frishman (NYMC: New York Medical College)H-Index: 65
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Ideal drugs to improve outcomes in type 2 diabetes mellitus (T2DM) are those with anti-glycemic efficacy, as well as cardiovascular safety that has to be determined in appropriately designed cardiovascular outcome trials as mandated by regulatory agencies. The more recent anti-hyperglycemic medications have shown promise with regards to cardiovascular disease (CVD) risk reduction in T2DM patients at a high cardiovascular risk. Sodium glucose cotransporter-2 inhibitors and glucagon-like peptide-1...
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#2George JollyH-Index: 2
Last. William H. FrishmanH-Index: 65
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Top fields of study
Cardiology
Intensive care medicine
Heart failure
Disease
Diabetes mellitus
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